GS70
GST P1-1, Recombinant Human
Synonym(e):
DFN7, FAEES3, GST3, GSTP, HEL-S-22, glutathione S-transferase pi
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Alle Fotos(1)
About This Item
UNSPSC-Code:
12352200
NACRES:
NA.26
Empfohlene Produkte
Biologische Quelle
human
Qualitätsniveau
Rekombinant
expressed in E. coli
Assay
>95% (SDS-PAGE)
Form
frozen liquid
Spezifische Aktivität
60.45 units/mg protein
Mol-Gew.
23 kDa
Lagertemp.
−70°C
Angaben zum Gen
human ... GSTP1(2950)
Allgemeine Beschreibung
using spectrophotometric determination of 1-chloro-2,4-dinitrobenzene (CDNB) conjugation with reduced glutathione (1.0 mM) in 100 mM KPO4 (pH 6.5) at room temperature.
Biochem./physiol. Wirkung
Glutathione S-transferase pi 1 (GSTP1) is an enzyme that in humans is encoded by the GSTP1 gene. Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. The GSTs are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
Lagerung und Haltbarkeit
The enzyme should be used by the end-user customer within 1 year of receipt.
Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 1
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Analysenzertifikate (COA)
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