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138630

Sigma-Aldrich

1-Chlor-2,4-dinitrobenzol

97%

Synonym(e):

2,4-Dinitro-chlorbenzol

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5 G
32,30 €
100 G
49,50 €
500 G
127,00 €

32,30 €

Versandbereit am23. April 2025Details

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5 G
32,30 €
100 G
49,50 €
500 G
127,00 €

About This Item

Lineare Formel:
ClC6H3(NO2)2
CAS-Nummer:
97-00-7
Molekulargewicht:
202.55
Beilstein:
613161
EG-Nummer:
202-551-4
MDL-Nummer:
MFCD00007075
UNSPSC-Code:
12352100
PubChem Substanz-ID:
24848362
NACRES:
NA.22

32,30 €

Versandbereit am23. April 2025Details

Bulk-Bestellung anfordern

Qualitätsniveau

100

Assay

97%

Form

solid

Expl.-Gr.

22 %

bp

315 °C (lit.)

mp (Schmelzpunkt)

48-50 °C (lit.)

Löslichkeit

alcohol: soluble (hot)
alcohol: very slightly soluble (cold)
benzene: soluble
carbon disulfide: soluble
diethyl ether: soluble
water: insoluble

Funktionelle Gruppe

chloro
nitro

SMILES String

[O-][N+](=O)c1ccc(Cl)c(c1)[N+]([O-])=O

InChI

1S/C6H3ClN2O4/c7-5-2-1-4(8(10)11)3-6(5)9(12)13/h1-3H

InChIKey

VYZAHLCBVHPDDF-UHFFFAOYSA-N

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Verwandte Kategorien

Anwendung

1-Chloro-2,4-dinitrobenzene was used in determination of relative amounts of individual glutathione S-transferases subunits in human tissues by reverse-phase HPLC[1]. It was used as contact sensitizer to study the antibacterial peptides hBD-2, -3 and -4 and LL-37 induced IL-18 protein release in human keratinocytes[2].

Biochem./physiol. Wirkung

2,4-dinitrochlorobenzene induces atopic dermatitis in BALB/c mice model[3].

Angaben zur Herstellung

The product is dissolved in ethanol when used as glutathione S-transferase substrate and then added to a buffer to form a final concentration of 1mM in phosphate buffer (8 mL of 0.2 M KH2PO4 and 28 mL of 0.1 M Na2HPO4 per 100 mL of solution, adjusted to pH 6.5) and 4% (v/v) ethanol.

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 2 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1

Lagerklassenschlüssel

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 2

Flammpunkt (°F)

381.2 °F - closed cup

Flammpunkt (°C)

194 °C - closed cup

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
STBL1466
STBK6718
STBK3781
STBK3548
STBK2336

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1-Fluor-2,4-Dinitrobenzol purum p.a., ≥98.0% (GC)

Sigma-Aldrich

42085

1-Fluor-2,4-Dinitrobenzol

1,4-Dinitrobenzol 98%

Sigma-Aldrich

102369

1,4-Dinitrobenzol

Mingli Sun et al.
Molecular medicine reports, 9(2), 689-694 (2013-12-18)
Bacillus Calmette-Guerin extract (BCGE) has been proven to be clinically effective for anaphylactic disease, infectious diseases and cancer. In this study, we investigated the effect of the intramuscular application of BCGE on 2,4-dinitrochlorobenzene (DNCB)-induced atopic dermatitis (AD). We established an
J D Rowe et al.
The Biochemical journal, 325 ( Pt 2), 481-486 (1997-07-15)
Uncertainties about the composition and identities of glutathione S-transferases (GSTs) in human tissue have impeded studies on their biological functions. A rigorous protocol has therefore been developed to characterize the human proteins. Cytosolic GST subunits were resolved by reverse-phase HPLC
Antony Anet et al.
Journal of hazardous materials, 370, 42-53 (2018-09-15)
This study investigates Bisphenol A (BPA) induced oxidative stress that mediates the genotoxicity in in vivo model Drosophila melanogaster. The calculated LC50 for BPA was 12.35 μg/mL. The strains of D. melanogaster were reared in 0.1, 1.0, 2.5 and 5.0 μg/mL BPA
François Niyonsaba et al.
Journal of immunology (Baltimore, Md. : 1950), 175(3), 1776-1784 (2005-07-22)
In addition to its physical barrier against invading microorganisms, the skin produces antimicrobial peptides, human beta-defensins (hBDs) and cathelicidin LL-37, that participate in the innate host defense. Because IL-18 is produced by keratinocytes and involved in skin diseases in which
Xiaoxiao Peng et al.
The Biochemical journal, 447(1), 167-174 (2012-07-13)
Thiophosphate (SPO(3)) was recently shown to promote cysteine insertion at Sec (selenocysteine)-encoding UGA codons during selenoprotein synthesis. We reported previously that irreversible targeting by cDDP [cis-diamminedichloroplatinum(II) or cisplatin] of the Sec residue in TrxR1 (thioredoxin reductase 1) contributes to cDDP
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Fragen

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 Antwort

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 Antwort

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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