B2417

Benzamil hydrochloride hydrate

≥98% (HPLC)

• Synonym(e): N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride hydrate
• Empirische Formel (Hill-System): C₁₃H₁₄ClN₇O · HCl · xH₂O
• CAS-Nummer: 161804-20-2
• Molekulargewicht: 356.21 (anhydrous basis)
• MDL-Nummer: MFCD28147597
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24278262
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: solid
• Lagerbedingungen: desiccated
• Farbe: yellow
• Löslichkeit: methanol: 10 mg/mL; DMSO: >20 mg/mL
• Lagertemp.: 2-8°C
• SMILES String: O.Cl.Nc1nc(N)c(nc1Cl)C(=O)NC(=N)NCc2ccccc2
• InChI: 1S/C13H14ClN7O.ClH.H2O/c14-9-11(16)20-10(15)8(19-9)12(22)21-13(17)18-6-7-4-2-1-3-5-7;;/h1-5H,6H2,(H4,15,16,20)(H3,17,18,21,22);1H;1H2
• InChIKey: YAJQRPFIYXRNKS-UHFFFAOYSA-N
• Angaben zum Gen: human ... SCNN1A(6337) , SCNN1B(6338) , SCNN1D(6339) , SCNN1G(6340) ; mouse ... Scnn1a(20276) , Scnn1b(20277) , Scnn1d(140501) , Scnn1g(20278) ; rat ... Scnn1a(25122) , Scnn1b(24767) , Scnn1g(24768)

Beschreibung

Biochem./physiol. Wirkung

Selective and potent blocker of Na⁺/H⁺ and Na⁺/Ca²⁺ channels

Leistungsmerkmale und Vorteile

This compound is featured on the Acid-Sensing (Proton-gated) Ion Channels (ASICs) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sonstige Hinweise

N_ω-Benzyl derivative of amiloride.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves