75068

9,10-Anthracendiyl-bis(methylen)dimalonsäure

BioReagent, suitable for fluorescence, ≥90% (HPCE)

• Synonym(e): ABDA, Single Oxygen Probe
• Empirische Formel (Hill-System): C₂₂H₁₈O₈
• CAS-Nummer: 307554-62-7
• Molekulargewicht: 410.37
• Beilstein: 3503804
• MDL-Nummer: MFCD03095464
• UNSPSC-Code: 12352106
• PubChem Substanz-ID: 329766104
• NACRES: NA.32

Eigenschaften

• Produktlinie: BioReagent
• Assay: ≥90% (HPCE)
• Form: powder
• Löslichkeit: DMSO: soluble
• Fluoreszenz: λ_ex 380 nm; λ_em 407 nm in 0.1 M phosphate pH 7.0
• Eignung: suitable for fluorescence
• SMILES String: OC(=O)C(Cc1c2ccccc2c(CC(C(O)=O)C(O)=O)c3ccccc13)C(O)=O
• InChI: 1S/C22H18O8/c23-19(24)17(20(25)26)9-15-11-5-1-2-6-12(11)16(10-18(21(27)28)22(29)30)14-8-4-3-7-13(14)15/h1-8,17-18H,9-10H2,(H,23,24)(H,25,26)(H,27,28)(H,29,30)
• InChIKey: DNUYOWCKBJFOGS-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

9,10-Anthracenediyl-bis(methylene)dimalonic acid or ABDA is a singlet oxygen probe.[1] It is highly fluorescent and soluble in water and binds to lipopolysaccharides (LPS) found in the cell membrane. 9,10-Anthracenediyl-bis(methylene)dimalonic acid takes four negative charges upon fully deprotonation in neutral aqueous solutions, stabilizing the ion-pair complex and facilitating selective recognition of LPS over other common ionic species of clinical significance. In addition to the emission maximum at 407 nm, there are lower maxima at 431, 457, and 485 nm.

Anwendung

9,10-Anthracenediyl-bis(methylene)dimalonic acid is widely used as a singlet oxygen detector probe. [1] 9,10-Anthracenediyl-bis(methylene)dimalonic acid is suitable for assessing the photodynamic effect of curcumin Vibrio parahaemolyticus, which is a significant cause of bacterial diarrhea.[2]

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Hinweis zur Analyse

Zusätzlich zum Emissionsmaximum bei 407 nm sind Nebenmaxima bei 431, 457 und 485 nm vorhanden.

Sonstige Hinweise

Reagenz zur Bestimmung von Singulett-Sauerstoff, mit besseren Eigenschaften als 9,10-Anthracendiyl-bis-dipropionsäure[3]

Sicherheitshinweise

• Piktogramme: GHS07,GHS09
• Signalwort: Warning
• H-Sätze: H315,H319,H335,H400
• P-Sätze: P261 - P264 - P271 - P273 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves