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PHR1476

Supelco

Diethyl-Phthalat

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(e):

Diethylphthalat, DEP

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About This Item

Lineare Formel:
C6H4-1,2-(CO2C2H5)2
CAS-Nummer:
Molekulargewicht:
222.24
Beilstein:
1912500
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

certified reference material
pharmaceutical secondary standard

Qualitätsniveau

Agentur

traceable to Ph. Eur. D1410000
traceable to USP 1193505

Dampfdichte

7.66 (vs air)

Dampfdruck

1 mmHg ( 100 °C)

API-Familie

diethyl phthalate

Analysenzertifikat (CofA)

current certificate can be downloaded

Selbstzündungstemp.

854 °F

Expl.-Gr.

0.75 %, 187 °F

Verpackung

pkg of 1 g

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Brechungsindex

n20/D 1.502 (lit.)

bp

298-299 °C (lit.)

mp (Schmelzpunkt)

−3 °C (lit.)

Dichte

1.12 g/mL at 25 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-30°C

SMILES String

CCOC(=O)c1ccccc1C(=O)OCC

InChI

1S/C12H14O4/c1-3-15-11(13)9-7-5-6-8-10(9)12(14)16-4-2/h5-8H,3-4H2,1-2H3

InChIKey

FLKPEMZONWLCSK-UHFFFAOYSA-N

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Allgemeine Beschreibung

Diethyl Phthalate is a phthalic acid ester, commonly synthesized by the condensation of the carboxy groups of phthalic acid with methanol.. It is used as a solvent for fragrance in cosmetic formulations and personal care products.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Anwendung

Diethyl Phthalate may be used as a pharmaceutical reference standard for the determination of the analyte in cosmetic products, pharmaceutical formulations and dietary supplements by chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAA3024 in the slot below. This is an example certificate only and may not be the lot that you receive.

Empfohlene Produkte

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

338.0 °F - closed cup

Flammpunkt (°C)

170 °C - closed cup


Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Gas chromatography in routine pharmaceutical analysis
Baines CB and Proctor KA
The Journal of Pharmacy and Pharmacology, 11(S1), 230T-234T (1959)
Phthalic Acid and Derivatives
Ullmann's Encyclopedia of Industrial Chemistry (2007)
Identification of phthalates in medications and dietary supplement formulations in the United States and Canada
Kelley K, et al.
Environmental Health Perspectives, 120(3), 379-384 (2011)
Analysis of consumer cosmetic products for phthalate esters.
Hubinger JC and Havery DC
Journal of Cosmetic Science, 57(2), 127-137 (2006)
Simultaneous determination of seven phthalates and four parabens in cosmetic products using HPLC-DAD and GC-MS methods
Shen Y-H, et al.
Journal of Separation Science, 30(1), 48-54 (2007)

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