PHR1366

Phthalsäuredibutylester

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(e): n-Butylphthalat, DBP, Dibutylphthalat
• Lineare Formel: C₆H₄-1,2-[CO₂(CH₂)₃CH₃]₂
• CAS-Nummer: 84-74-2
• Molekulargewicht: 278.34
• Beilstein: 1914064
• EG-Nummer: 201-557-4
• MDL-Nummer: MFCD00009441
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329823345
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material; pharmaceutical secondary standard
• Qualitätsniveau: 300
• Agentur: traceable to Ph. Eur. D1010000; traceable to USP 1187080
• Dampfdichte: 9.6 (vs air)
• Dampfdruck: 1 mmHg ( 147 °C)
• API-Familie: dibutyl phthalate
• Analysenzertifikat (CofA): current certificate can be downloaded
• Selbstzündungstemp.: 756 °F
• Expl.-Gr.: 0.47 %, 236 °F
• Verpackung: pkg of 1 g
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• Brechungsindex: n20/D 1.492 (lit.)
• bp: 340 °C (lit.)
• mp (Schmelzpunkt): −35 °C (lit.)
• Dichte: 1.043 g/mL at 25 °C (lit.)
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: 2-30°C
• SMILES String: CCCCOC(=O)c1ccccc1C(=O)OCCCC
• InChI: 1S/C16H22O4/c1-3-5-11-19-15(17)13-9-7-8-10-14(13)16(18)20-12-6-4-2/h7-10H,3-6,11-12H2,1-2H3
• InChIKey: DOIRQSBPFJWKBE-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Dibutyl Phthalate is a diester of phthalate, commonly synthesized by the condensation of the carboxy groups of phthalic acid with two molecules of 1-butanol. It is used as a plasticizer and film coating agent in solid pharmaceutical dosage forms.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Anwendung

Dibutyl Phthalate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and dietary supplements by chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Weichmacher

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAA1470 in the slot below. This is an example certificate only and may not be the lot that you receive.

Sicherheitshinweise

• Piktogramme: GHS08,GHS09
• Signalwort: Danger
• H-Sätze: H360FD,H410
• P-Sätze: P202 - P273 - P280 - P308 + P313 - P391 - P405
• Gefahreneinstufungen: Aquatic Acute 1 - Aquatic Chronic 2 - Repr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): 339.8 °F
• Flammpunkt (°C): 171 °C