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Merck

439215

Sigma-Aldrich

Tetrahydrofuran

≥99.9%, suitable for HPLC, inhibitor-free

Synonym(e):

Butylenoxid, Oxolan, Tetramethylenoxid

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About This Item

Empirische Formel (Hill-System):
C4H8O
CAS-Nummer:
Molekulargewicht:
72.11
Beilstein:
102391
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12190000
PubChem Substanz-ID:
bp:
65-67 °C (lit.)
Preise und Verfügbarkeit sind derzeit nicht verfügbar.

Produktbezeichnung

Tetrahydrofuran, suitable for HPLC, ≥99.9%, inhibitor-free

Qualität

HPLC grade

Qualitätsniveau

Dampfdichte

2.5 (vs air)

Dampfdruck

114 mmHg ( 15 °C)
143 mmHg ( 20 °C)

Assay

≥99.9%

Form

liquid

Selbstzündungstemp.

610 °F

Expl.-Gr.

1.8-11.8 %

Methode(n)

HPLC: suitable

Verunreinigungen

≤0.015% peroxide (as H2O2)
<0.02% water

Abdampfrückstand

<0.0005%

Brechungsindex

n20/D 1.407 (lit.)

bp

65-67 °C (lit.)

mp (Schmelzpunkt)

−108 °C (lit.)

Löslichkeit

H2O: soluble

Dichte

0.889 g/mL at 25 °C (lit.)

λ

H2O reference

UV-Absorption

λ: 212 nm Amax: 1.0
λ: 250 nm Amax: 0.180
λ: 300 nm Amax: 0.020
λ: 350-400 nm Amax: 0.005

SMILES String

C1CCOC1

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2

InChIKey

WYURNTSHIVDZCO-UHFFFAOYSA-N

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Allgemeine Beschreibung

Tetrahydrofuran (THF) is a saturated cyclic ether with a potential use as a biofuel. Its combustion studies have been reported.[1] Reports suggest it is a better promoter than 1,3 dioxolane for CO2-hydrate formation.[2] The effect of THF on the biological systems has been studied.[3]

Anwendung

Tetrahydrofuran may be used as a solvent in the following processes:
  • Formation of diacetylinic polymers.[4]
  • RAFT polymerization of p-acetoxystyrene.[5]
  • Synthesis of di-tert-butyl-Phosphinoferrocene.[6]
It may be used in the following processes:
  • As mobile phase solvent in high-performance liquid chromatography.[7]
  • As a solvent in the preparation of spin-coated poly(bisphenol A decane ether).[8]
  • Formation of butyrolactone (BTL) by green oxidation method.[9]
  • As a solvent for lignin depolymerization to isolate phenolic monomer.[10]

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Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Zielorgane

Central nervous system, Respiratory system

Zusätzliche Gefahrenhinweise

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 1

Flammpunkt (°F)

-6.2 °F - closed cup

Flammpunkt (°C)

-21.2 °C - closed cup

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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1 of 3

Solène I Cauët et al.
Journal of polymer science. Part A, Polymer chemistry, 48(12), 2517-2524 (2010-07-27)
The kinetics of the RAFT polymerization of p-acetoxystyrene using a trithiocarbonate chain transfer agent, S-1-dodecyl-S'-(α,α'-dimethyl-α″-acetic acid)trithiocarbonate, DDMAT, was investigated. Parameters including temperature, percentage initiator, concentration, monomer-to-chain transfer agent ratio and solvent were varied and their impact on the rate of
Novel Diacetylinic Aryloxysilane Polymers: A New Thermally Cross-Linkable High Temperature Polymer System.
Drake K, et al.
Macromolecules, 46(11), 4370-4377 (2013)
Oxidation of tetrahydrofuran to butyrolactone catalyzed by iron-containing clay.
Ausavasukhi A and Sooknoi T.
Green Chemistry, 17(1), 435-441 (2015)
1,3 Dioxolane versus tetrahydrofuran as promoters for CO2-hydrate formation: Thermodynamics properties, and kinetics in presence of sodium dodecyl sulfate.
Torre JP, et al.
Chemical Engineering Science, 126, 688-697 (2015)
Practical Synthesis of Di-tert-Butyl-Phosphinoferrocene.
Busacca CA, et al.
Organic Syntheses, 90, 316-326 (2013)

Artikel

Polar graphitic carbon enables UHPLC separation of highly polar pesticides, herbicides, and Vitamin D metabolites, advancing liquid chromatography capabilities.

Fragen

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 Antwort
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 Antwort
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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