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Merck

38266

Millipore

Ferrioxamin E aus Streptomyces antibioticus

suitable for microbiology, ≥95%

Synonym(e):

1,12,23-Trihydroxy-1,6,12,17,23,28-hexaazacyclotritriacontan-2,5,13,16,24,27-hexon Eisen(III)-Komplex

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About This Item

Empirische Formel (Hill-System):
C27H45FeN6O9
CAS-Nummer:
Molekulargewicht:
653.53
MDL-Nummer:
UNSPSC-Code:
41171614
PubChem Substanz-ID:
NACRES:
NA.85

Sterilität

non-sterile

Qualitätsniveau

Assay

≥95% (HPLC)
≥95%

Form

powder

Verlust

≤6% loss on drying

Anwendung(en)

environmental
food and beverages

microbiology

Lagertemp.

2-8°C

Eignung

Salmonella spp.

SMILES String

[Fe+3].[O-]N1CCCCCNC(=O)CCC(=O)N([O-])CCCCCNC(=O)CCC(=O)N([O-])CCCCCNC(=O)CCC1=O

InChI

1S/C27H45N6O9.Fe/c34-22-10-14-26(38)32(41)20-8-3-6-18-30-24(36)12-15-27(39)33(42)21-9-2-5-17-29-23(35)11-13-25(37)31(40)19-7-1-4-16-28-22;/h1-21H2,(H,28,34)(H,29,35)(H,30,36);/q-3;+3

InChIKey

MZFKJKOHYACYNT-UHFFFAOYSA-N

Verwandte Kategorien

Allgemeine Beschreibung

Scientifically proven supplement for culture media improves detection of Salmonella, Enterobacter sakazakii and Yersinia enterocolitica .

Ferrioxamine E from Streptomyces antibioticum is a siderophore which facilitates the supply of iron (III), an essential trace element, to bacteria involved in food poisoning, including Salmonella, Enterobacter saka-zakii and Yersinia enterocolitica. It promotes rapid growth by reducing the lag phase in culture media and reactivates dormant bacteria. Use of ferrioxamine E can permit rapid detection of low bacterial cell counts, even from dry products like spices and tea after long storage periods. It is an essential component of quality control efforts in the food industry.

Ferrioxamine E is often used in Buffered Peptone Water, the medium recommended by the ISO-Norms for Enterobacteriacea. Ferrioxamine E also improves the motility of Salmonella, which helps to improve the identification by semisolid selective motility media like SIM, MRSV, DIASSALM or SMS. Ferrioxamine E does not improve growth of Escherichia coli, Shigella, Proteus, Providencia and Morganella species; a feature that makes it a semi-selective compound. The recommended concentration of Ferrioxamine E to promote bacterial growth is between 5 and 200 ng/mL
The ferrioxamines are basically metabolic products produced by the actinomycetes, and are characterised as ferrioxamines A, B, C, D 1, D2, E, F and G. Generally all ferrioxamines are trihydroxamates and the deferrioxamines are either linear or cyclic (D2 and E).

Anwendung

Der Zusatz von Ferrioxamin E in Voranreicherungsbouillons und Anreicherungsbouillons erhöht die Wiederfindungsrate von Salmonellen aus natürlich und unnatürlich kontaminierten Nahrungsmitteln signifikant.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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H Heinonen-Tanski et al.
Microbiological research, 155(1), 65-68 (2000-06-01)
The effect of a siderophoric compound, ferrioxamine E, in the pre-enrichment broth on determining of Salmonella infantis in environmental samples was tested with combination of various pre-enrichment times and enrichment temperatures of 37 and 43 degrees C. Ferrioxamine E slightly
The crystal structure of ferrioxamine E
Helm VD
Journal of the American Chemical Society, 98 (1) (1976)
R Reissbrodt et al.
Zentralblatt fur Bakteriologie : international journal of medical microbiology, 279(3), 344-353 (1993-08-01)
Salmonella can overcome the iron limitation of iron-limited nutrient media and albumen by utilizing the siderophores ferrioxamine E and G und grow. 14 out of 18 food-poisoning Salmonella strains of different serotypes stored in hen's egg albumen (approx. 2 organisms/ml)
R Reissbrodt et al.
Applied and environmental microbiology, 68(10), 4788-4794 (2002-09-27)
Salmonella enterica serovar Typhimurium and enterohemorrhagic Escherichia coli were stressed by prolonged incubation in water microcosms until it was no longer possible to observe colony formation when samples were plated on nonselective medium. Overnight incubation of samples in nutrient-rich broth
Milos Petrik et al.
Nuclear medicine and biology, 39(3), 361-369 (2011-12-17)
Siderophores are low-molecular-mass iron chelators serving as iron transporters for almost all bacteria, fungi and some plants. Iron is an essential element for majority of organisms and plays an important role in virulence of pathogenic organisms. (68)Ga is a positron

Artikel

Microbiological assessment of bacteria found in spices, a potent source for food spoilage and pathogens.

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