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Merck

10784

Sigma-Aldrich

Antipyrin

tested according to Ph. Eur.

Synonym(e):

Phenazonum, 2,3-Dimethyl-1-phenyl-3-pyrazolin-5-on, Phenazon

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About This Item

Empirische Formel (Hill-System):
C11H12N2O
CAS-Nummer:
Molekulargewicht:
188.23
Beilstein:
157775
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.21

Agentur

USP/NF
tested according to Ph. Eur.

Qualitätsniveau

Form

crystals and lumps
powder

mp (Schmelzpunkt)

109-111 °C (lit.)

Löslichkeit

H2O: soluble 1 gm in less than 1ml
alcohol: soluble 1 gm in 1.3 ml
chloroform: soluble 1 gm in 1 ml
diethyl ether: soluble 1 gm in 43 ml

Anwendung(en)

pharmaceutical (small molecule)

SMILES String

CN1N(C(=O)C=C1C)c2ccccc2

InChI

1S/C11H12N2O/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3

InChIKey

VEQOALNAAJBPNY-UHFFFAOYSA-N

Angaben zum Gen

human ... PTGS1(5742)

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Anwendung

Antipyrine has been used for immunoblotting. It has also been used as an internal reference marker for studying the transport characteristics of platinum-containing drug, cisplatin in the human placenta in vitro.

Biochem./physiol. Wirkung

Antipyrine also referred to as phenazone or phenazonum is an anti-inflammatory agent that possesses analgesic, antipyretic and platelet-inhibitory actions.

Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Eyad Al-Saleh et al.
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Platinum-containing drugs are used extensively in the treatment of various malignancies in humans. Data are scarce on the maternal-fetal transport characteristics in humans of one such widely used drug, cisplatin, and this prompted us to study its transport characteristics in
E Girbal-Neuhauser et al.
Journal of immunology (Baltimore, Md. : 1950), 162(1), 585-594 (1999-01-14)
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Factors influencing antipyrine elimination.
I H Stevenson
British journal of clinical pharmacology, 4(3), 261-265 (1977-06-01)
Antipyrine as a model drug to study hepatic drug-metabolizing capacity.
H E Poulsen et al.
Journal of hepatology, 6(3), 374-382 (1988-06-01)

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