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700143P

Avanti

27-alkyne cholesterol

Avanti Research™ - A Croda Brand 700143P, powder

Synonym(e):

27-alkyne cholesterol

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About This Item

Empirische Formel (Hill-System):
C28H44O
CAS-Nummer:
1527467-07-7
Molekulargewicht:
396.65
MDL-Nummer:
MFCD34621711
UNSPSC-Code:
12352211
NACRES:
NA.25
Preise und Verfügbarkeit sind derzeit nicht verfügbar.

Assay

>99% (TLC)

Form

powder

Verpackung

pkg of 1 × 1 mg (700143P-1MG)
pkg of 1 × 100 μg (700143P-100ug)
pkg of 1 × 250 μg (700143P-250ug)

Hersteller/Markenname

Avanti Research™ - A Croda Brand 700143P

Versandbedingung

dry ice

Lagertemp.

−20°C

Allgemeine Beschreibung

Alkyne cholesterol is used to trace cholesterol metabolism and localization.[1]
This reagent is a modified lipid containing an omega-terminal alkyne. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents, known as ‘click chemistry′, in the presence of a copper (Cu)-containing catalyst.

Biochem./physiol. Wirkung

27-alkyne cholesterol acts similar to natural sterols such as, ergosterol and cholesterol.[2]

Verpackung

5 mL Amber Glass Screw Cap Vial (700143P-1MG)
5 mL Amber Glass Screw Cap Vial (700143P-100ug)
5 mL Amber Glass Screw Cap Vial (700143P-250ug)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Analysenzertifikate (COA)

Lot/Batch Number

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A novel alkyne cholesterol to trace cellular cholesterol metabolism and localization.
Hofmann K, et al.
Journal of Lipid Research, 55(3), 583-591 (2014)
Kristina Hofmann et al.
Journal of lipid research, 55(3), 583-591 (2013-12-18)
Cholesterol is an important lipid of mammalian cells and plays a fundamental role in many biological processes. Its concentration in the various cellular membranes differs and is tightly regulated. Here, we present a novel alkyne cholesterol analog suitable for tracing
Yaroslav V Faletrov et al.
Chemistry and physics of lipids, 227, 104850-104850 (2019-12-15)
20-hydroxycholesterol is a signaling oxysterol with immunomodulating functions and, thus, structural analogues with reporter capabilities could be useful for studying and modulating the cellular processes concerned. We have synthesized three new 20-hydroxycholesterol-like pregn-5-en-3β-ol derivatives with fluorescent 7-nitrobenzofurazan (NBD) or Raman-sensitive

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