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Merck

G6104

Sigma-Aldrich

Glycinamid -hydrochlorid

98%

Synonym(e):

2-Aminoacetamide hydrochloride, Aminoacetamide hydrochloride, Glycine amide hydrochloride

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About This Item

Lineare Formel:
NH2CH2CONH2 · HCl
CAS-Nummer:
Molekulargewicht:
110.54
Beilstein:
3554199
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.22

Assay

98%

mp (Schmelzpunkt)

204 °C (dec.) (lit.)

SMILES String

Cl.NCC(N)=O

InChI

1S/C2H6N2O.ClH/c3-1-2(4)5;/h1,3H2,(H2,4,5);1H

InChIKey

WKNMKGVLOWGGOU-UHFFFAOYSA-N

Anwendung

Buffer useful in the physiological pH range.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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As a model for mechanistic comparison with peptidyl transfer within the ribosome, the reaction of aqueous glycinamide with N-formylphenylalanine trifluoroethyl ester (fPhe-TFE) represents an improvement over earlier model reactions involving Tris. The acidity of trifluoroethanol (pKa 12.4) resembles that of
Carolina García-Martínez et al.
The journal of pain : official journal of the American Pain Society, 7(10), 735-746 (2006-10-05)
Vanilloid receptor subunit 1 (TRPV1) is an integrator of physical and chemical stimuli in the peripheral nervous system. This receptor plays a key role in the pathophysiology of inflammatory pain. Thus, the identification of receptor antagonists with analgesic and anti-inflammatory
Lihu Yang et al.
Bioorganic & medicinal chemistry letters, 16(14), 3735-3739 (2006-05-16)
Systematic modification of a screening lead yielded a class of potent glycinamide based CCR2 antagonists. The best compound (55, (2S)-N-[3,5-bis(trifluoromethyl)benzyl]-2-{[2-(1-piperidinyl)ethyl]amino}-2-(3-thienyl)acetamide) displayed good binding affinity (IC50=30 and 39 nM) toward human monocytes and CHO cell expressing human CCR2b, respectively. Functionally, it
Yong Sun et al.
The journal of physical chemistry. B, 109(12), 5919-5926 (2006-07-21)
For the purpose of investigating the tautomerism from glycinamide (G) to glycinamidic acid (G*) induced by proton transfer, we carried out a study of structural interconversion of the two tautomers and the relative stabilizing influences of water during the tautomerization
Len Ito et al.
FEBS letters, 585(3), 555-560 (2011-01-18)
Glycine amide (GlyAd), a typically amidated amino acid, is a versatile additive that suppresses protein aggregation during refolding, heat treatment, and crystallization. In spite of its effectiveness, the exact mechanism by which GlyAd suppresses protein aggregation remains to be elucidated.

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