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Merck

A8309

Sigma-Aldrich

Acethydrazid

90%

Synonym(e):

Acetylhydrazin, Essigsäurehydrazid

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About This Item

Lineare Formel:
CH3CONHNH2
CAS-Nummer:
Molekulargewicht:
74.08
Beilstein:
506165
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.22
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Assay

90%

Form

flakes

Verunreinigungen

<10% acetic acid

bp

129 °C/18 mmHg (lit.)

mp (Schmelzpunkt)

58-68 °C (lit.)

SMILES String

CC(=O)NN

InChI

1S/C2H6N2O/c1-2(5)4-3/h3H2,1H3,(H,4,5)

InChIKey

OFLXLNCGODUUOT-UHFFFAOYSA-N

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Allgemeine Beschreibung

Acethydrazide is an organic building that undergo catalytic hydrogenation to produce N′-methyl acethydrazide (MAH).[1]

Anwendung

Acethydrazide can be used in the synthesis of (E)-N′-(2-hydroxybenzylidene)acetohydrazide, an ONO pincer ligand.[2]

Piktogramme

Skull and crossbonesHealth hazard

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flammpunkt (°F)

235.4 °F - closed cup

Flammpunkt (°C)

113 °C - closed cup

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Kunden haben sich ebenfalls angesehen

Analysis of isoniazid, acetylhydrazine and [15N2]acetylhydrazine in serum by capillary gas chromatography-ammonia chemical ionization mass spectrometry.
G Karlaganis et al.
Journal of chromatography, 420(1), 171-177 (1987-09-04)
Liquid phase hydrogenation of acethydrazone to N'-methyl acethydrazide over Pd/?-Al2O3 catalyst
Pakdehi SG, et al.
Brazilian Journal of Chemical Engineering, 27, 145-152 (2010)
A Walubo et al.
Methods and findings in experimental and clinical pharmacology, 20(8), 649-655 (1999-01-29)
Isoniazid and its metabolites acetylisoniazid, hydrazine and monoacetylhydrazine were investigated for generation of oxygen free radicals during incubation with rat liver slices. Lipid peroxidation was assessed by the thiobarbituric acid reactive substances test using malonaldehyde as the external standard, while
T C Sarich et al.
Archives of toxicology, 70(12), 835-840 (1996-01-01)
Isoniazid (INH) continues to be a highly effective drug in the chemoprophylaxis and treatment of tuberculosis; however, its use is associated with hepatotoxicity (predominantly hepatic necrosis) in 1-2% of individuals. The INH metabolites, acetylhydrazine and hydrazine, have each been implicated
N E Preece et al.
Journal of chromatography, 573(2), 227-234 (1992-01-17)
Plasma and liver levels of hydrazine were determined at 10, 30, 90 and 270 min in rats given 0.09, 0.27, 0.84 and 2.53 mmol of hydrazine per kg body weight orally by capillary gas chromatography-mass spectrometry of its pentafluorobenzaldehyde adduct

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 Antwort
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 Antwort
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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