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Journal of controlled release : official journal of the Controlled Release Society, 320, 412-420 (2020-02-06)
Cytosolic protein delivery is important for the development of protein therapeutics towards intracellular targets. Guanidyl polymers exhibit high binding affinity with cargo proteins, and thus were designed as carriers for intracellular protein delivery. However, the structure-activity relationship and mechanism of
Journal of pharmaceutical and biomedical analysis, 109, 79-84 (2015-03-15)
In this paper, novel LC-MS/MS methods for the determination of antiepileptic drug pregabalin in dried matrix spots (DMS) are presented. This attractive technique of sample collection in micro amount was utilized in the form of dried blood spots (DBS) and
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 962, 102-108 (2014-06-09)
This paper presents a LC-MS/MS method for the determination of antiepileptic drug vigabatrin in dried plasma spots (DPS). Due to its zwitterionic chemical structure, a pre-column derivatization procedure was performed, aiming to yield enhanced ionization efficiency and improved chromatographic behaviour.
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