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Merck

729108

Sigma-Aldrich

Poly(ethylenglycol)methyletherthiol

average MN 800, chemical modification reagent thiol reactive, methoxy, thiol

Synonym(e):

Methoxy-PEG-thiol, Methoxypolyethylenglykol-thiol, PEG-thiol, mPEG-thiol

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1 G
273,00 €
5 G
961,00 €

273,00 €


Versandbereit am14. April 2025Details


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1 G
273,00 €
5 G
961,00 €

About This Item

Lineare Formel:
CH3O(CH2CH2O)nCH2CH2SH
UNSPSC-Code:
12162002
NACRES:
NA.23

273,00 €


Versandbereit am14. April 2025Details


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Produktbezeichnung

Poly(ethylenglycol)methyletherthiol, average Mn 800

Form

solid

Mol-Gew.

average Mn 800

Eignung der Reaktion

reagent type: chemical modification reagent
reactivity: thiol reactive

Verunreinigungen

≤10% disulfide

Übergangstemp.

Tm 32-37 °C

Mw/Mn

≤1.1

Ω-Ende

thiol

α-Ende

methoxy

Polymerarchitektur

shape: linear
functionality: monofunctional

Lagertemp.

2-8°C

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Anwendung

Poly(ethylenglycol)methyletherthiol kann verwendet werden, um Fe3O4@Au Kern-Schale-Nanopartikel zu funktionalisieren. Das thiolierte PEG erhöht die Wasserlöslichkeit und senkt die Nanotoxizität signifikant.

Es kann als Vorläufer für die Synthese von PEG-konjugierten Poly(β-aminoester)polyplexen für die Gentherapie eingesetzt werden.

Piktogramme

Exclamation mark

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3


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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Nisha C. Kalarickal, Stephen Rimmer, Prodip Sarker, and Jean-Christophe Leroux
Macromolecules, 40, 1874-1874 (2007)
Cristina Gentilini, Mariangela Boccalon, and Lucia Pasquato
The Journal of Organic Chemistry, 3308-3308 (2008)

Artikel

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Fragen

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 Antwort
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 Antwort
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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