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47316

Sigma-Aldrich

Fmoc-D-Leu-OH

≥95.0% (TLC)

Synonym(e):

Fmoc-D-leucin

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About This Item

Empirische Formel (Hill-System):
C21H23NO4
CAS-Nummer:
114360-54-2
Molekulargewicht:
353.41
Beilstein:
4299950
MDL-Nummer:
MFCD00062957
UNSPSC-Code:
12352209
eCl@ss:
32160406
PubChem Substanz-ID:
57650921
NACRES:
NA.26

Assay

≥95.0% (TLC)

Eignung der Reaktion

reaction type: Fmoc solid-phase peptide synthesis

Anwendung(en)

peptide synthesis

Funktionelle Gruppe

Fmoc

Lagertemp.

2-8°C

SMILES String

CC(C)C[C@@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O

InChI

1S/C21H23NO4/c1-13(2)11-19(20(23)24)22-21(25)26-12-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h3-10,13,18-19H,11-12H2,1-2H3,(H,22,25)(H,23,24)/t19-/m1/s1

InChIKey

CBPJQFCAFFNICX-LJQANCHMSA-N

Verwandte Kategorien

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

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Fmoc-Leu-OH Novabiochem®

Sigma-Aldrich

8.52011

Fmoc-Leu-OH

Fmoc-D-Ser(tBu)-OH ≥98.0% (TLC)

Sigma-Aldrich

47311

Fmoc-D-Ser(tBu)-OH

Fmoc-D-Thr(tBu)-OH ≥98.0% (TLC)

Sigma-Aldrich

47312

Fmoc-D-Thr(tBu)-OH

Fmoc-D-Ala-OH Novabiochem®

Sigma-Aldrich

8.52142

Fmoc-D-Ala-OH

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Sigma-Aldrich

47561

Fmoc-Trp(Boc)-OH

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Sigma-Aldrich

47623

Fmoc-Tyr(tBu)-OH

Zhimou Yang et al.
Chemical communications (Cambridge, England), (35)(35), 4414-4416 (2005-09-02)
Two types of therapeutic agents, which have discrete yet complementary functions, self-assemble into nanofibers in water to formulate a new supramolecular hydrogel as a self-delivery biomaterial to reduce the toxicity of uranyl oxide at the wound sites.
G Cheng et al.
Langmuir : the ACS journal of surfaces and colloids, 26(7), 4990-4998 (2010-01-16)
The self-assembly and hydrogelation properties of two Fmoc-tripeptides [Fmoc = N-(fluorenyl-9-methoxycarbonyl)] are investigated, in borate buffer and other basic solutions. A remarkable difference in self-assembly properties is observed comparing Fmoc-VLK(Boc) with Fmoc-K(Boc)LV, both containing K protected by N(epsilon)-tert-butyloxycarbonate (Boc). In
Chung-Ren Jan et al.
The Chinese journal of physiology, 45(3), 117-122 (2003-06-24)
In Madin-Darby canine kidney (MDCK) cells, effect of NPC-15199 on intracellular Ca2+ concentration ([Ca2+]i) was investigated by using fura-2. NPC-15199 (100-1000 microM) caused a rapid and sustained increase of [Ca2+]i in a concentration-dependent manner (EC50=500 microM). NPC-15199-induced [Ca2+]i rise was
C R Jan et al.
The Chinese journal of physiology, 43(1), 29-33 (2000-06-17)
This report demonstrates that NPC-15199 [(N-(9-fluorenylmethoxycarbonyl)L-leucine)], a novel anti-inflammatory agent, increases intracellular Ca2+ concentration ([Ca2+]i) in human bladder female transitional cancer (BFTC) cells. Using fura-2 as a Ca2+ probe, NPC-15199 (0.1-2 mM) was found to increase [Ca2+]i concentration-dependently. The response
M J Miller et al.
The Journal of pharmacology and experimental therapeutics, 266(1), 468-472 (1993-07-01)
Anti-inflammatory properties have been ascribed to a series of N-(fluorenyl-9-methoxycarbonyl) amino acids called leumedins that inhibit the activity of granulocytes and T-lymphocytes. We evaluated one of these leumedins, N-(fluorenyl-9-methoxycarbonyl) leucine (NPC 15199), in a model of ileitis in guinea pigs.
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