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  • Asymmetric assembly of 2-oxindole and α-angelica lactone units to construct vicinal quaternary chiral centers.

Asymmetric assembly of 2-oxindole and α-angelica lactone units to construct vicinal quaternary chiral centers.

Chemical communications (Cambridge, England) (2012-01-24)
Xin Huang, Jin Peng, Lin Dong, Ying-Chun Chen
ANOTACE

The first organocatalytic asymmetric assembly of Morita-Baylis-Hillman carbonates of isatins and α-angelica lactone has been studied, affording multifunctional products containing two valuable pharmacophores and vicinal quaternary chiral centers in high stereoselectivity (up to 92% ee, dr >95:5).

MATERIÁLY
Číslo produktu
Značka
Popis produktu

Sigma-Aldrich
2-Oxindole, 97%
Sigma-Aldrich
α-Angelica lactone, 98%, FG
Sigma-Aldrich
α-Angelica lactone, 98%