Přejít k obsahu
Merck
Všechny fotografie(1)

Key Documents

1672257

USP

Topotecan hydrochloride

United States Pharmacopeia (USP) Reference Standard

Synonyma:

(S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione monohydrochloride, NSC 609669

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen
Všechny fotografie(1)

About This Item

Empirický vzorec (Hillův zápis):
C23H23N3O5 · HCl
Číslo CAS:
1067286-75-2
Molekulová hmotnost:
457.91
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

topotecan

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

InChI

1S/C23H23N3O5.ClH/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20;/h5-8,27,30H,4,9-11H2,1-3H3;1H/t23-;/m0./s1

Inchi Key

DGHHQBMTXTWTJV-BQAIUKQQSA-N

Hledáte podobné produkty? Navštivte Průvodce porovnáváním produktů

Související kategorie

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Topotecan hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

pictograms

Health hazard
GHS08

signalword

Danger

Hazard Classifications

Muta. 1B - Repr. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Osvědčení o analýze (COA)

Vyhledejte osvědčení Osvědčení o analýze (COA) zadáním čísla šarže/dávky těchto produktů. Čísla šarže a dávky lze nalézt na štítku produktu za slovy „Lot“ nebo „Batch“.

Již tento produkt vlastníte?

Dokumenty související s produkty, které jste v minulosti zakoupili, byly za účelem usnadnění shromážděny ve vaší Knihovně dokumentů.

Navštívit knihovnu dokumentů

Zákazníci si také prohlíželi

Slide 1 of 10

1 of 10

USP

USP

1347609

Irinotecan hydrochloride

Melphalan powder

Sigma-Aldrich

M2011

Melphalan

β-D-Ribofuranose 1-acetate 2,3,5-tribenzoate 98%

Sigma-Aldrich

159018

β-D-Ribofuranose 1-acetate 2,3,5-tribenzoate

Cytarabine European Pharmacopoeia (EP) Reference Standard

C3350000

Cytarabine

Carvacrol natural, 99%, FG

Sigma-Aldrich

W224511

Carvacrol

Imipramine hydrochloride BioXtra, ≥99% (TLC)

Sigma-Aldrich

I0899

Imipramine hydrochloride

(S)-(+)-Camptothecin ≥90% (HPLC), powder

Sigma-Aldrich

C9911

(S)-(+)-Camptothecin

Tamoxifen analytical standard

Supelco

85256

Tamoxifen

Cyclophosphamide Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1404

Cyclophosphamide

Cisplatin British Pharmacopoeia (BP) Reference Standard

BP809

Cisplatin

Vishnu Suresh Babu et al.
Cancers, 14(20) (2022-10-28)
Advanced retinoblastoma (Rb) tumors display high metastatic spread to distant tissues, causing a potent threat to vision and life. Through transcriptomic profiling, we discovered key upregulated genes that belonged to the epithelial-mesenchymal transition (EMT) and chemotherapy resistance pathways in advanced
Vishnu Suresh Babu et al.
Pharmaceutics, 14(11) (2022-11-27)
Host defense peptides represent an important component of innate immunity. In this work, we report the anticancer properties of a panel of hyper-charged wholly cationic antimicrobial dodecapeptides (CAPs) containing multiple canonical forms of lysine and arginine residues. These CAPs displayed
Kathryn S Evans et al.
Genetics, 210(4), 1509-1525 (2018-10-21)
Phenotypic complexity is caused by the contributions of environmental factors and multiple genetic loci, interacting or acting independently. Studies of yeast and Arabidopsis often find that the majority of natural variation across phenotypes is attributable to independent additive quantitative trait
Hajera Amatullah et al.
Cell, 185(17), 3232-3247 (2022-08-12)
How mis-regulated chromatin directly impacts human immune disorders is poorly understood. Speckled Protein 140 (SP140) is an immune-restricted PHD and bromodomain-containing epigenetic "reader," and SP140 loss-of-function mutations associate with Crohn's disease (CD), multiple sclerosis (MS), and chronic lymphocytic leukemia (CLL).
Mahendra Jadhao et al.
Antioxidants (Basel, Switzerland), 10(6) (2021-07-03)
The characteristics of phthalates had been thought to be similar to endocrine disruptors, which increases cancer risk. The role of phthalates in acquired drug resistance remains unclear. In this study, we investigated the effect of di-(2-ethylhexyl) phthalate (DEHP) on acquired

Náš tým vědeckých pracovníků má zkušenosti ve všech oblastech výzkumu, včetně přírodních věd, materiálových věd, chemické syntézy, chromatografie, analytiky a mnoha dalších..

Obraťte se na technický servis.