1066009

Betamethasone

United States Pharmacopeia (USP) Reference Standard

• Synonyma: 9α-Fluoro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16β-methylprednisolone
• Empirický vzorec (Hillův zápis): C₂₂H₂₉FO₅
• Číslo CAS: 378-44-9
• Molekulová hmotnost: 392.46
• MDL number: MFCD00062969
• UNSPSC Code: 41116107
• PubChem Substance ID: 329748930
• NACRES: NA.24

Vlastnosti

• biological source: synthetic
• grade: pharmaceutical primary standard
• agency: USP
• vapor pressure: <0.0000001 kPa ( 25 °C)
• API family: betamethasone
• packaging: pkg of 200 mg
• manufacturer/tradename: USP
• color: white to off-white
• mp: 235-237 °C (lit.); 447.8-473 °F (231—245°C; decomposes)
• solubility: acetone: sparingly soluble; chloroform: very slightly soluble; ethanol: sparingly soluble; ether: very slightly soluble; methanol: sparingly soluble; water: insoluble
• density: 0.305 g/cm³ at 25 °C (77°F)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: [H][C@@]12C[C@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C
• InChI: 1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
• InChI key: UREBDLICKHMUKA-DVTGEIKXSA-N
• Gene Information: human ... NR3C1(2908)

Popis

General description

Betamethasone, a synthetic glucocorticoid, belongs to the corticosteroid family of active pharmaceutical ingredients (APIs).
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Betamethasone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Betamethasone Acetate
• Betamethasone Oral Solution
• Betamethasone Valerate Cream
• Betamethasone Valerate Lotion
• Betamethasone Valerate Ointment
• Dexamethasone

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Bezpečnostní informace

• pictograms: GHS08
• signalword: Danger
• hcodes: H360FD,H373
• pcodes: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1B - STOT RE 2
• target_organs: Liver,Kidney,Endocrine system
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable