This product is not food grade or pharmaceutical grade. Please see the following links to review Vitamin E options which are suitable for pharmaceutical manufacturing:
https://www.sigmaaldrich.com/product/mm/500862
https://www.sigmaaldrich.com/product/mm/500859
https://www.sigmaaldrich.com/product/mm/500878
https://www.sigmaaldrich.com/product/mm/500949
T3251
(±)-α-Tocopherol
synthetic, ≥96% (HPLC)
Synonyma:
DL-all-rac-α-Tocopherol, Vitamin E
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Vybrat velikost
Změnit zobrazení
| Vám/Skladová položka | Dostupnost | Cena |
|---|---|---|
5 g | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 886,00 Kč |
25 g | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 2 740,00 Kč |
100 g | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 6 310,00 Kč |
500 g | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 20 200,00 Kč |
O této položce
Empirický vzorec (Hillův zápis):
C29H50O2
Číslo CAS:
Molekulová hmotnost:
430.71
NACRES:
NA.77
PubChem Substance ID:
eCl@ss:
34058016
UNSPSC Code:
12352205
EC Number:
233-466-0
MDL number:
Beilstein/REAXYS Number:
94012
886,00 Kč
Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.
Technický servis
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Dovolte nám, abychom vám pomohlibiological source
synthetic
Quality Segment
assay
≥96% (HPLC)
form
liquid
technique(s)
HPLC: suitable
color
faint brown to brown, yellow to very dark yellow
solubility
H2O: insoluble, acetone: miscible, chloroform: miscible, ethanol: miscible, vegetable oils: miscible
density
0.950 g/mL at 20 °C (lit.)
storage temp.
2-8°C
SMILES string
CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1
InChI
1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3
InChI key
GVJHHUAWPYXKBD-UHFFFAOYSA-N
Application
(±)-α-Tocopherol has been used for preparing mycobacterial emulsions. It has also been used to study its immunomodulatory effect on influenza virus.
Biochem/physiol Actions
Tocopherols (vitamin E) comprise of a series (α, β, γ and δ) of chiral compounds that differ by the methylation degree of the phenol moiety of the chromanol ring. They function as lipid soluble antioxidants and protect cell membranes from oxidative damage. α-tocopherols are favorably absorbed by humans and their nicotinate salts can function as vitamin E supplements. Studies have also reported that vitamin E can prevent cell damage caused by pharmacologically induced epilepsy in rats.
Preparation Note
(±)-α-Tocopherol is miscible with chloroform, ethanol, ether, acetone, and vegetable oils. However, it is practically insoluble in water. (±)-α-Tocopherol is unstable under alkaline conditions.
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Tato položka | |||
|---|---|---|---|
| technique(s) HPLC: suitable | technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable | technique(s) HPLC: suitable, gas chromatography (GC): suitable | technique(s) - |
| biological source synthetic | biological source - | biological source - | biological source - |
| assay ≥96% (HPLC) | assay - | assay - | assay - |
| form liquid | form liquid | form - | form viscous liquid |
| storage temp. 2-8°C | storage temp. −70°C | storage temp. 2-8°C | storage temp. 15-25°C |
| solubility H2O: insoluble, chloroform: miscible, vegetable oils: miscible, acetone: miscible, ethanol: miscible | solubility - | solubility - | solubility - |
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signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
Skladovací třída
10 - Combustible liquids
wgk
WGK 1
ppe
Eyeshields, Gloves
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Is this Vitamin E product food grade or pharmaceutical grade? And where is document showing the grade of the product?
1 answer-
Helpful?
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How can I determine the shelf life / expiration / retest date of this product?
1 answer-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
Helpful?
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What is the concentration of item T3251 (W/V)?
1 answer-
The material is a neat or pure liquid, undiluted with a solvent. At a purity of 100%, the molarity is 2.205 M. The minimum purity specification for this product is 96%. The molarity will vary from lot to lot based on the determined purity. For a lot of this product with a minimum purity of 96%, the molarity will be 2.117 M.
Helpful?
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Hi. Could you please provide the concentration of this product (w/v)? Thanks!
1 answer-
This material is a neat or pure liquid that has not been diluted with a solvent. At a purity of 100%, the molarity is 2.205 M. The minimum purity specification for this product is 96%. The molarity will change from lot to lot based on the determined purity. A lot of this product with a minimum purity of 96% will be 2.117 M. Please see the link below to review a sample or lot specific Certificate of Analysis:
https://www.sigmaaldrich.com/product/sigma/t3251#product-documentationHelpful?
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Hi, I would like to ask if you have the LC-MS grade of this chemical (Tocopherol CAS number; 10191-41-0, part no: T3251-5G). I'm in need of the LC-MS authentic standard of this chemical to compare my isolated compound with. Thank you.
1 answer-
This product is not considered a standard nor has it been tested for use as such in LC-MS. Product number V-020 is a 1 mg/mL α-tocopherol solution in methanol. This product is a certified reference material suitable for use as a standard in HPLC or LC-MS/MS.
Please see the link below to review this product option:
https://www.sigmaaldrich.com/product/cerillian/v020Helpful?
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