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T3165

Sigma-Aldrich

7-Methoxy-4-(trifluoromethyl)coumarin

≥99% (TLC)

Synonyma:

Methyl 4-(trifluoromethyl)umbelliferyl ether

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About This Item

Empirický vzorec (Hillův zápis):
C11H7F3O3
Číslo CAS:
575-04-2
Molekulová hmotnost:
244.17
Beilstein/REAXYS Number:
225039
MDL number:
MFCD00132980
UNSPSC Code:
12352204
PubChem Substance ID:
24900113
NACRES:
NA.32

assay

≥99% (TLC)

form

powder

solubility

acetone: 50 mg/mL, clear, colorless to faintly yellow

fluorescence

λex 333 nm; λem 416 nm in methanol

SMILES string

COc1ccc2c(OC(=O)C=C2C(F)(F)F)c1

InChI

1S/C11H7F3O3/c1-16-6-2-3-7-8(11(12,13)14)5-10(15)17-9(7)4-6/h2-5H,1H3

InChI key

HAZHUELNIGDYQH-UHFFFAOYSA-N

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Application

7-Methoxy-4-(trifluoromethyl)coumarin has been used as a substrate in cytochrome P450 2E1 (CYP2E1) activity assay and aromatase assay.

Biochem/physiol Actions

The enzymatic action of cytochrome P450 2E1 (CYP2E1) on 7-methoxy-4-(trifluoromethyl)coumarin results in a fluorescent product 7-hydroxy-4-(trifluoromethyl)coumarin (HFC) that can be measured at 409/530 nm.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

Osvědčení o analýze (COA)

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