SML3439

IXA4

98% (HPLC)

• Synonyma: N-​Methyl-​N-​[2-​(4-​methylphenoxy)​ethyl]​-​4-​[(1-​oxo-​3-​phenoxypropyl)​amino]​-1H-​pyrazole-​1-​acetamide
• Empirický vzorec (Hillův zápis): C₂₄H₂₈N₄O₄
• Číslo CAS: 1185329-96-7
• Molekulová hmotnost: 436.50
• MDL number: MFCD13023943
• UNSPSC Code: 12352200
• NACRES: NA.77

Vlastnosti

• Quality Level: 100
• assay: 98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: −20°C
• SMILES string: O=C(CN1N=CC(NC(CCOC2=CC=CC=C2)=O)=C1)N(C)CCOC3=CC=C(C=C3)C

Popis

Biochem/physiol Actions

IXA4 is a nontoxic, potent and highly selective IRE1-XBP1s signaling activator that induce ER proteostasis remodeling. IXA4 reduced Aβ levels and prevents APP-associated mitochondrial dysfunction in CHO7PA2 cells expressing the V717F APP (APPV717F) mutant.

Bezpečnostní informace

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable