RAB0820

Mouse Lepr / Leptin Receptor ELISA Kit

• UNSPSC Code: 41116158
• NACRES: NA.32

Vlastnosti

• species reactivity: mouse
• packaging: kit of 96 wells (12 strips x 8 wells)
• technique(s): ELISA: suitable
• input: sample type cell culture supernatant(s); sample type serum; sample type plasma
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 32 pg/mL; standard curve range: 32.77-8000 pg/mL
• detection method: colorimetric
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: mouse ... Lepr(16847)

Popis

General description

The antibody pair provided in this kit recognizes mouse Leptin Receptor.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Leptin receptor (Lepr) belonging to class I cytokine receptor family, binds with leptin, a small non-glycosylated peptide hormone and transduces signal. Lepr expression is present in brain and immune cells. Signal transduction through Lepr regulates fat metabolism in mammals. Lepr is part of the hematopoietic pathway. Lepr is a marker for mesenchymal stem/stromal cells (MSCs) and regulates the regenerative process of bone and cartilage after injury. Lepr regulates pancreatic β cell functions. Polymorphism in Lepr causes metabolic diseases like obesity, dyslipidemia, hypertension and Type 2 diabetes. Mutations in Lepr associates with polycystic ovarian syndrome (PCOS) susceptibility.

Součásti soupravy, které jsou dostupné také samostatně

• RABTMB3 ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
• RABSTOP3 ELISA Stop Solution (Item I)
• RABWASH4 20X Wash Buffer (Item B)

Bezpečnostní informace

• pictograms: GHS05
• signalword: Warning
• hcodes: H290
• pcodes: P234 - P390
• Hazard Classifications: Met. Corr. 1
• Storage Class: 8A - Combustible corrosive hazardous materials
• flash_point_f: Not applicable
• flash_point_c: Not applicable