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Key Documents

RAB0332

Sigma-Aldrich

Human Lipocalin-2 / NGAL ELISA Kit

for serum, plasma, cell culture supernatant and urine

Synonyma:

Lipocalin-2, NGAL, Neutrophil gelatinase-associated lipocalin 

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen


About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type serum
sample type plasma
sample type cell culture supernatant(s)
sample type urine

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 4 pg/mL
standard curve range: 4.1-1000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... LCN2(3934)

General description

Lipocalin-2 (LCN2), a secreted glycoprotein, is an adipokine. It is expressed in various cells like respiratory cells, intestinal epithelial cells, endothelial cells, renal tubular cells and cardiomyocytes. The gene LCN2 is located on human chromosome 9q34. The human lipocalin-2 ELISA (enzyme-linked immunosorbent assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human lipocalin-2 in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human Lipocalin-2

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human Lipocalin-2/NGAL ELISA Kit has been used in the electrochemical immunoassay. It has also been used to determine the neutrophil gelatinase-associated lipocalin (NGAL) levels in the urine.

Biochem/physiol Actions

Lipocalin-2 (LCN2) has been implicated in a variety of processes including cell differentiation, tumorigenesis and apoptosis. Polymorphisms in the expression of LCN2 are associated with many cancers such as breast, colorectal, pancreatic, ovarian, gastric, thyroid, ovarian, bladder and kidney cancers.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Součásti soupravy, které jsou dostupné také samostatně

Č. produktu
Popis
Bezpečností list

  • RABELADEELISA 5X Assay/Sample Diluent Buffer E (Item E2)Bezpečností list

  • RABSTOP3ELISA Stop Solution (Item I)Bezpečností list

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)Bezpečností list

  • RABWASH420X Wash Buffer (Item B)Bezpečností list

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials


Osvědčení o analýze (COA)

Vyhledejte osvědčení Osvědčení o analýze (COA) zadáním čísla šarže/dávky těchto produktů. Čísla šarže a dávky lze nalézt na štítku produktu za slovy „Lot“ nebo „Batch“.

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Navštívit knihovnu dokumentů

Ai-Li Sun et al.
Mikrochimica acta, 187(9), 485-485 (2020-08-07)
An innovative signal-transduction tag based on cross-linked urease nanoparticles (CLENP) was designed for the development of a pH meter-based immunoassay of lipocalin-2 (LCN2). The CLENP was synthesized with a typical desolvation method using ethanol as desolvation agent, followed by functionalization with polyaspartic
Expression of neutrophil gelatinase-associated lipocalin in colorectal neoplastic progression: a marker of malignant potential?
McLean MH
British Journal of Cancer, 108, 2537-2537 (2013)
Julio Cezar Q Machado et al.
Journal of physical activity & health, 15(9), 679-682 (2018-08-03)
Neutrophil gelatinase-associated lipocalin (NGAL) is a glycoprotein released during early phases of a postischemic kidney in response to kidney injury, inflammation, and oxidative stress. It can be detected in urine after 2 hours of an ischemic event. The aim was
Network based analyses of gene expression profile of LCN2 overexpression in esophageal squamous cell carcinoma
Wu B, et al.
Scientific Reports, 5403-5403 (2014)
Quantification of NGAL in Urine of Endurance Cycling Athletes
Machado J C Q, et al.
Journal of physical activity & health, 15(9), 679-682 (2018)

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