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RAB0160

Sigma-Aldrich

Human EGFR / ErbB1 ELISA Kit

for serum, plasma, cell culture supernatants and urine

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen


About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type urine
sample type cell culture supernatant(s)
sample type plasma
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 4 pg/mL
standard curve range: 2.74-2000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... EGFR(1965)

General description

Epidermal growth factor receptor (EGFR) is a member of the epidermal growth factor receptor tyrosine kinase (RTK) family. It is a single-chain transmembrane glycoprotein. EGFR comprises an extracellular ligand-binding ectodomain, a short juxtamembrane section, a transmembrane domain, a tyrosine kinase domain, tyrosine-containing C-terminal tail. Overexpression of EGFR is observed in breast cancer cells.

Immunogen

Recombinant Human EGFR

Application

Human EGFR / ErbB1 ELISA Kit has been used in the estimation of epidermal growth factor receptors (EGFR) from human epithelial cells. It has also been used in the detection of EGFR from patient plasma/serum and exosomes isolated from human prostate cancer cells LNCaP xenografts.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Součásti soupravy, které jsou dostupné také samostatně

Č. produktu
Popis
Bezpečností list

  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)Bezpečností list

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)Bezpečností list

  • RABSTOP3ELISA Stop Solution (Item I)Bezpečností list

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)Bezpečností list

  • RABWASH420X Wash Buffer (Item B)Bezpečností list

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials


Vyberte jednu z posledních verzí:

Osvědčení o analýze (COA)

Lot/Batch Number

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Potřebujete-li konkrétní verzi, můžete vyhledat daný certifikát podle čísla dávky nebo čísla šarže.

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Navštívit knihovnu dokumentů

Geetanjali Kharmate et al.
PloS one, 11(5), e0154967-e0154967 (2016-05-07)
Exosomes proteins and microRNAs have gained much attention as diagnostic tools and biomarker potential in various malignancies including prostate cancer (PCa). However, the role of exosomes and membrane-associated receptors, particularly epidermal growth factor receptor (EGFR) as mediators of cell proliferation
Lingmei Huang et al.
Scientific reports, 7(1), 11084-11084 (2017-09-13)
Biomass fuel smoke is thought to contribute to chronic obstructive pulmonary disease, which is characterized by mucous cell metaplasia and enhanced mucus secretion. We investigated the effect of particulate matter (PM) with a diameter <2.5 μm (PM2.5) from wood smoke
Chung-Ming Huang et al.
PloS one, 12(7), e0180604-e0180604 (2017-07-13)
We have previously described the association of rheumatoid arthritis (RA) prevalence and two epidermal growth factor receptor (EGFR) SNPs (rs17337023 and rs2227983) among the Taiwanese population. This present study aimed to elucidate whether the SNPs can alter the expression of
Takumi Fujiwara et al.
Cancers, 12(10) (2020-10-25)
Background: Lung cancer is the leading cause of mortality for cancer worldwide. A point mutation in exon 21 of the epidermal growth factor receptor resulting in the substitution of arginine for leucine at position 858 (L858R) is a frequent cause
Yi Zhao et al.
Cancer research, 80(11), 2217-2229 (2020-03-21)
Stemness and epithelial-mesenchymal transition (EMT) are two fundamental characteristics of metastasis that are controlled by diverse regulatory factors, including transcription factors. Compared with other subtypes of breast cancer, basal-type or triple-negative breast cancer (TNBC) has high frequencies of tumor relapse.

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