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C5360

SAFC

L-Cysteine

Farmaceutická výroba

Synonyma:

(R)-2-Amino-3-mercaptopropionic acid

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About This Item

Lineární vzorec:
HSCH2CH(NH2)CO2H
Číslo CAS:
52-90-4
Molekulová hmotnost:
121.16
Beilstein/REAXYS Number:
1721408
EC Number:
200-158-2
MDL number:
MFCD00064306
UNSPSC Code:
12352209
eCl@ss:
32160406
NACRES:
NA.26

biological source

non-animal source

Quality Level

400

form

crystalline powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, heavy metals, trace metals, tested

mp

240 °C (dec.) (lit.)

solubility

H2O: 25 mg/mL

suitability

suitable for manufacturing use

foreign activity

cytotoxicity, tested

SMILES string

N[C@@H](CS)C(O)=O

InChI

1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1

InChI key

XUJNEKJLAYXESH-REOHCLBHSA-N

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Související kategorie

General description

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to the documentation for this product requires a confidentiality disclosure agreement.

Application

L-Cysteine is a non-essential amino acid. It is commonly used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Biochem/physiol Actions

NMDA glutamatergic receptor agonist.

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Vyberte jednu z posledních verzí:

Osvědčení o analýze (COA)

Lot/Batch Number
CDBG6617
CDBG6597
CDBG6616
CDBG5751
CDBG6141

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Potřebujete-li konkrétní verzi, můžete vyhledat daný certifikát podle čísla dávky nebo čísla šarže.

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L-Aspartic acid

SAFC

A5474

L-Aspartic acid

L-Cysteine, Free Base Naturally-occurring non-essential amino acid.

Millipore

243005

L-Cysteine, Free Base

L-Arginine

SAFC

A4474

L-Arginine

L-Cysteine hydrochloride monohydrate from non-animal source, suitable for cell culture, meets EP, USP testing specifications

Sigma-Aldrich

C6852

L-Cysteine hydrochloride monohydrate

D-Cysteine ≥99% (RT)

Sigma-Aldrich

30095

D-Cysteine

L-Tyrosine

SAFC

T4321

L-Tyrosine

Nicholas Kwiatkowski et al.
Nature, 511(7511), 616-620 (2014-07-22)
Tumour oncogenes include transcription factors that co-opt the general transcriptional machinery to sustain the oncogenic state, but direct pharmacological inhibition of transcription factors has so far proven difficult. However, the transcriptional machinery contains various enzymatic cofactors that can be targeted
Eun Young Park et al.
Journal of agricultural and food chemistry, 62(26), 6183-6189 (2014-06-01)
The present study examined the impact of the supplementation of glutathione (GSH), γ-L-glutamyl-L-cysteinyl-glycine, on human blood GSH levels. Healthy human volunteers were orally supplemented with GSH (50 mg/kg body weight). Venous blood was collected from the cubital vein before and
Takeshi Annoura et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(5), 2158-2170 (2014-02-11)
The 10 Plasmodium 6-Cys proteins have critical roles throughout parasite development and are targets for antimalaria vaccination strategies. We analyzed the conserved 6-cysteine domain of this family and show that only the last 4 positionally conserved cysteine residues are diagnostic
John Gilchrist et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(51), E5016-E5024 (2013-12-04)
Voltage-gated sodium (Nav) channels are embedded in a multicomponent membrane signaling complex that plays a crucial role in cellular excitability. Although the mechanism remains unclear, β-subunits modify Nav channel function and cause debilitating disorders when mutated. While investigating whether β-subunits
Georg K A Hochberg et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(16), E1562-E1570 (2014-04-09)
Mammalian small heat-shock proteins (sHSPs) are molecular chaperones that form polydisperse and dynamic complexes with target proteins, serving as a first line of defense in preventing their aggregation into either amorphous deposits or amyloid fibrils. Their apparently broad target specificity
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Sortimentní položky

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

Chromatograms

application for HPLC

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