A5139

Asp-Phe methyl ester

≥98%

• Synonyma: N-(L-α-Aspartyl)-L-phenylalanine methyl ester, Asp-Phe-OMe, Aspartame
• Lineární vzorec: HOOCCH₂CH(NH₂)CONHCH(CH₂C₆H₅)COOCH₃
• Číslo CAS: 22839-47-0
• Molekulová hmotnost: 294.30
• Beilstein/REAXYS Number: 2223850
• EC Number: 245-261-3
• MDL number: MFCD00002724
• UNSPSC Code: 12352108
• PubChem Substance ID: 24890947
• NACRES: NA.26

Vlastnosti

• product name: Asp-Phe methyl ester, ≥98%
• assay: ≥98%
• form: powder
• sweetness: 160-200 × sucrose
• color: white to off-white
• storage temp.: 2-8°C
• SMILES string: COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(O)=O
• InChI: 1S/C14H18N2O5/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18)/t10-,11-/m0/s1
• InChI key: IAOZJIPTCAWIRG-QWRGUYRKSA-N

Popis

General description

Asp-Phe methyl ester (aspartame, APM, ASP), a dipeptide ester, is made up of phenyl alanine and aspartic acid. Its genotoxic effects have been investigated. Its interaction with certain hydrocolloids has been studied.

Application

Asp-Phe methyl ester is used for the preparation of Ad libitum Standard Chow, with ad libitum drinking water (animals control diet) containing Asp-Phe methyl ester. It is also used for the TFA diet preparation (TFA diet with ad lib drinking water contains Asp-Phe methyl ester.

Biochem/physiol Actions

Asp-Phe methyl ester (Asp-Phe-OMe) is used as a synthetic sweeter, sugar substitute. Asp-Phe methyl ester is being studied for a variety of potential benefits as a nutrition supplement, such as the delay of osteoarthritis and modulation of rheumatoid factor activity. Asp-Phe methyl ester is being studied for its effect on thrombin activity and blood clotting.

Bezpečnostní informace

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)