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Y0001139

Epinastine hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonyma:

9,13b-Dihydro-1H-dibenz[cf]imidazo[1,5-a]azepine hydrochloride, WAL-801Cl

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About This Item

Empirický vzorec (Hillův zápis):
C16H15N3 · HCl
Číslo CAS:
108929-04-0
Molekulová hmotnost:
285.77
MDL number:
MFCD00933434
UNSPSC Code:
41116107
PubChem Substance ID:
329830781
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

epinastine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cl[H].NC1=NCC2N1c3ccccc3Cc4ccccc24

InChI

1S/C16H15N3.ClH/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16;/h1-8,15H,9-10H2,(H2,17,18);1H

InChI key

VKXSGUIOOQPGAF-UHFFFAOYSA-N

Gene Information

human ... HRH1(3269)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Epinastine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Epinastine hydrochloride is a non-sedating H1 histamine receptor antagonist.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Č. produktu
Popis
Stanovení ceny

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Osvědčení o analýze (COA)

Lot/Batch Number

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Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 102(6), 495-499 (2009-06-30)
Nonsedating antihistamines (nsAHs) are recommended as first-line therapeutics for the treatment of mast cell-driven disorders, including allergic rhinitis and urticaria. However, their superiority over first-generation AHs (fgAHs) has recently been called into question, mainly because of the lack of supporting
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International journal of pharmaceutics, 441(1-2), 121-127 (2012-12-19)
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Expert opinion on drug metabolism & toxicology, 5(9), 1135-1140 (2009-07-28)
Epinastine is a topical ophthalmic antihistamine and a mast cell stabilizer indicated for treatment of symptoms associated with allergic conjunctivitis. The objective of this review is to provide a comprehensive overview of the pharmacology, clinical efficacy, tolerability and safety of
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