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T2550000

Tris Base

solid, pharmaceutical primary standard, European Pharmacopoeia (EP) Reference standard

Synonyma:

Tromethamine, 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Tris(hydroxymethyl)aminomethane, Trometamol, Tris

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About This Item

Empirický vzorec (Hillův zápis):
C4H11NO3
Číslo CAS:
77-86-1
Molekulová hmotnost:
121.14
EC Number:
201-064-4
MDL number:
MFCD00004679
UNSPSC Code:
41116107
PubChem Substance ID:
329826713
NACRES:
NA.24

product name

Trometamol, European Pharmacopoeia (EP) Reference Standard

grade

pharmaceutical primary standard

API family

trometamol, tromethamine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

NC(CO)(CO)CO

InChI

1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2

InChI key

LENZDBCJOHFCAS-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia.

For further information and support please go to the website of the issuing Pharmacopoeia.

Application

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia. Their suitability for any other use is not guaranteed and is the sole responsibility of the user. This standard is not intended for human or animal use.
Established for use in the identification of trometamol using Infra-red absorption spectroscopy and preparation of reference solution (a) to test related substances in trometamol using thin-layer chromatography (General text 2.2.27), as per monograph 1053 of European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Osvědčení o analýze (COA)

Lot/Batch Number

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Tris(hydroxymethyl)aminomethane (Trometamol), EMPROVE® EXPERT, Ph. Eur., BP, ChP, JPC, USP

SAFC

1.08386

Tris(hydroxymethyl)aminomethane

Tris(hydroxymethyl)aminomethane ACS reagent, ≥99.8%

Sigma-Aldrich

252859

Tris(hydroxymethyl)aminomethane

Trizma® base Primary Standard and Buffer, ≥99.9% (titration), crystalline

Sigma-Aldrich

T1503

Trizma® base

Sucrose European Pharmacopoeia (EP) Reference Standard

S1600000

Sucrose

Glycine European Pharmacopoeia (EP) Reference Standard

G0450000

Glycine

Trizma® base BioPerformance Certified, meets EP, USP testing specifications, suitable for cell culture, ≥99.9% (titration)

Sigma-Aldrich

T6066

Trizma® base

Iron(II) ethylenediammonium sulfate tetrahydrate 98%

Sigma-Aldrich

414913

Iron(II) ethylenediammonium sulfate tetrahydrate

Trometamol
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 4107-4108 (2017)
Corey A Baron et al.
Magnetic resonance in medicine, 73(3), 1075-1084 (2014-04-12)
An acquisition method that does not increase scan time or specific absorption rate is investigated for reducing the deleterious effects of cerebrospinal fluid (CSF) partial volume effects on diffusion tensor imaging (DTI) tractography. It is based on using a shorter
Filippo Bertoli et al.
Small (Weinheim an der Bergstrasse, Germany), 10(16), 3307-3315 (2014-04-17)
Nanoparticles in contact with cells and living organisms generate quite novel interactions at the interface between the nanoparticle surface and the surrounding biological environment. However, a detailed time resolved molecular level description of the evolving interactions as nanoparticles are internalized
D R Brocks et al.
Clinical pharmacokinetics, 23(6), 415-427 (1992-12-01)
Ketorolac is a new chiral nonsteroidal anti-inflammatory drug (NSAID) which is marketed for analgesia as the racemate. The drug is administered as the water soluble tromethamine salt and is available in tablets or as an intramuscular injection. The absorption of
S S Patel et al.
Drugs, 53(4), 637-656 (1997-04-01)
Fosfomycin tromethamine is a phosphonic acid bactericidal agent with in vitro activity against most urinary tract pathogens. It is particularly active against Escherichia coli, and Citrobacter, Enterobacter, Klebsiella, Serratia and Enterococcus spp. There appears to be little cross-resistance between fosfomycin
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