A pure, 200 Proof Ethanol should be used to dilute this material.
O1008
Oleic acid
≥99% (GC)
1 of 1 reviewers received a sample product or took part in a promotion
Synonyma:
9Z-Octadecenoic acid, cis-Oleic acid, cis-9-Octadecenoic acid, Elainic acid
Přihlásit pro zobrazení organizačních a smluvních cen.
Vybrat velikost
Změnit zobrazení
| Vám/SKU | Dostupnost | Cena |
|---|---|---|
1 g | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 1 640,00 Kč |
5 g | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 5 050,00 Kč |
25 g | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 17 300,00 Kč |
O této položce
Lineární vzorec:
CH3(CH2)7CH=CH(CH2)7COOH
Číslo CAS:
Molekulová hmotnost:
282.46
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
EC Number:
204-007-1
Beilstein/REAXYS Number:
1726542
MDL number:
1 640,00 Kč
Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.
Technický servis
Potřebujete pomoc? Náš tým zkušených odborníků je vám k dispozici.
Dovolte nám, abychom vám pomohlibiological source
plant (Sunflower)
Quality Segment
vapor pressure
1 mmHg ( 176 °C)
assay
≥99% (GC)
form
viscous liquid
color
colorless to very faintly yellow
refractive index
n20/D 1.459 (lit.)
bp
194-195 °C/1.2 mmHg (lit.)
mp
13-14 °C (lit.)
solubility
H2O: insoluble (practically), alcohol: soluble, benzene: soluble, chloroform: soluble, oil: soluble (fixed and volatile)
density
0.89 g/mL at 25 °C (lit.)
application(s)
life science and biopharma
lipidomics
functional group
oleic acid
lipid type
unsaturated FAs
shipped in
ambient
storage temp.
−20°C
SMILES string
CCCCCCCC\C=C/CCCCCCCC(O)=O
InChI
1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9-
InChI key
ZQPPMHVWECSIRJ-KTKRTIGZSA-N
Gene Information
human ... PRKCA(5578), PRKCB(5579), PRKCD(5580), PRKCE(5581), PRKCG(5582), PRKCH(5583), PRKCI(5584), SOAT1(6646), SOAT2(8435)
General description
Oleic acid (OA), a non-essential fatty acid, is classified as monounsaturated fatty acid (MUFA) richly present in olive oil. Its quantitative removal from the mixtures of triglyceride and partial glycerides has been reported. OA is widely used as a surfactant for the stabilization of magnetic nanoparticles. Monodisperse magnetite nanoparticles (7 and 19nm) coated with OA have been prepared.
Application
Oleic acid has been used:
- to study the effects of fatty acids on gastric cancer (GC)
- to induce lipid droplet formation in cell culture
- as an additive in the magnetorheological fluid preparation.
Biochem/physiol Actions
Oleic acid is known to improve immune function and health. Dietary supplement of this fatty acid contributes to the reduction in cholesterol levels, atherogenesis risk, blood pressure, and host versus graft response. Oleic acid has been proven to benefit autoimmune diseases by exhibiting anti-inflammatory action. It also ameliorates the condition of breast cancer. Oleic acid produces physiological effects such as protein kinase C activation in hepatocytes, uncoupling oxidative phosphorylation, and 2,4-dinitrophenol−stimulated ATPase inhibition. This action can be reversed by adding serum albumin.
Other Notes
For additional information on our range of Biochemicals, please complete this form.
1 of 1
Tato položka | |||
|---|---|---|---|
| description ≥99% (GC) | description meets analytical specification of Ph, Eur., 65.0-88.0% (GC) | description natural, FCC | description technical grade, 90% |
| functional group oleic acid | functional group carboxylic acid | functional group - | functional group oleic acid |
| biological source plant (Sunflower) | biological source - | biological source - | biological source plant |
| assay ≥99% (GC) | assay 65.0-88.0% (GC) | assay - | assay 90% |
| solubility chloroform: soluble, alcohol: soluble, oil: soluble (fixed and volatile), benzene: soluble, H2O: insoluble (practically) | solubility - | solubility - | solubility water: insoluble, diethyl ether: soluble, chloroform: soluble, alcohol: soluble, benzene: soluble |
| shipped in ambient | shipped in - | shipped in - | shipped in ambient |
| form viscous liquid | form liquid | form liquid | form waxy solid, liquid, semisolid |
Still not finding the right product?
Explore all of our products under Oleic acid
Skladovací třída
10 - Combustible liquids
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
flash_point_f
>235.4 °F - closed cup
flash_point_c
> 113 °C - closed cup
Vyberte jednu z posledních verzí:
Již tento produkt vlastníte?
Dokumenty související s produkty, které jste v minulosti zakoupili, byly za účelem usnadnění shromážděny ve vaší Knihovně dokumentů.
-
How much percentage ethanol should be used for dissolving oleic acid?
1 answer-
Helpful?
-
-
Should oleic acid be dissolved in ethanol and then administered to the cell culture, or can it be added directly to the culture medium? If it can be added directly, how should this be done? In addition, is conjugation with bovine serum albumin (BSA) neces
1 answer-
Oleic acid is a fatty acid and is not very soluble in aqueous solutions. To improve solubility, it is often recommended to dissolve oleic acid in a suitable organic solvent (like ethanol or DMSO) before adding it to the culture medium. This helps achieve a more uniform distribution in the medium. If adding directly to the culture medium without prior dissolution, it is advisable to use a small amount of heat (e.g., warming to 37°C) to help dissolve the oleic acid. However, this method may not yield complete solubility and could lead to uneven distribution.
Helpful?
-
-
How can I determine the shelf life / expiration / retest date of this product?
1 answer-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdfHelpful?
-
-
Can be used in mice?
1 answer-
This product is not tested for use in research animals such as mice. But there certainly is precedence for its use by researchers in a mouse model:
1. https://pubmed.ncbi.nlm.nih.gov/32663612/
See Table 1.
2. https://pubmed.ncbi.nlm.nih.gov/37380774/
See Methods section.Helpful?
-
-
How to store the product after opening the amplue?
1 answer-
The stability of this product in solution has not been determined. However, cell culture supplements containing Oleic acid, available as sterile solutions, are stored at 2-8°C and assigned a shelf life of 1 year. See the table below:
Helpful?
-
-
How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
Helpful?
-
-
What solvent is used to resuspend oleic acid in this product?
1 answer-
This product is a neat or pure liquid that has not been diluted. The recommended solvents are ethanol, methanol, chloroform, and benzene. This information is listed in the 'PROPERTIES' section of the product page.
Helpful?
-
-
What sort of packaging for the vial do you offer ?
1 answer-
The packaging varies according to the quanitity. The 1G package is in a 5 mL clear glass, flat bottom, sealed ampule. The 5G package is in a 10 mL clear glass, flat bottom, sealed ampule. The 25G package is in a 50 mL clear glass, flat bottom, sealed ampule.
Helpful?
-
-
Hello, would OA be soluble in DMSO? Also, after diluting in solvent, how long can it be stored in -20?
1 answer-
Oleic acid is completely miscible with Dimethyl sulfoxide (DMSO) in all proportions. It is generally not recommended to store solutions of unsaturated fatty acids such as oleic acid, due to oxidation. But if the solution is stored under an inert gas (e.g., nitrogen gas or argon gas), that would extend the stability of the solution.
The exact amount of time that the solution is stable is undetermined. Evidence for instability of the solution would be a change in color (colorless to yellow, or yellow to dark yellow, or dark yellow to brown).
Helpful?
-
-
How to sterilize pure oleic acid?
1 answer-
This product can be sterilized by autoclaving. When diluted in medium or buffer to a working concentration, solutions can be filter-sterilized.
Helpful?
-
