C2170000

Cilastatin sodium

European Pharmacopoeia (EP) Reference Standard

• Synonyma: Cilastatin sodium salt
• Empirický vzorec (Hillův zápis): C₁₆H₂₅N₂NaO₅S
• Číslo CAS: 81129-83-1
• Molekulová hmotnost: 380.43
• UNSPSC Code: 41116107
• NACRES: NA.24

Vlastnosti

• grade: pharmaceutical primary standard
• API family: cilastatin
• manufacturer/tradename: EDQM
• application(s): pharmaceutical (small molecule)
• format: neat
• InChI: 1S/C16H26N2O5S.Na/c1-16(2)8-10(16)13(19)18-12(15(22)23)6-4-3-5-7-24-9-11(17)14(20)21;/h6,10-11H,3-5,7-9,17H2,1-2H3,(H,18,19)(H,20,21)(H,22,23);/q;+1/p-1/b12-6-;/t10-,11+;/m1./s1
• InChI key: QXPBTTUOVWMPJN-QBNHLFMHSA-M

Popis

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Cilastatin sodium EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Inhibitor of the renal enzyme dehydropeptidase I and some bacterial zinc-containing β-lactamases. By these action, cilastatin suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Bezpečnostní informace

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable