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A0230000

Adenine

European Pharmacopoeia (EP) Reference Standard

Synonyma:

6-Aminopurine, Vitamin B4

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About This Item

Empirický vzorec (Hillův zápis):
C5H5N5
Číslo CAS:
73-24-5
Molekulová hmotnost:
135.13
Beilstein/REAXYS Number:
5777
MDL number:
MFCD00041790
UNSPSC Code:
41116107
PubChem Substance ID:
329770588
NACRES:
NA.24

biological source

synthetic

grade

pharmaceutical primary standard

agency

EP

API family

adenine

form

solid

manufacturer/tradename

EDQM

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp

>360 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Nc1ncnc2[nH]cnc12

InChI

1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10)

InChI key

GFFGJBXGBJISGV-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. Adenine belongs to the group of purine alkaloids widely distributed in plant products and beverages. It can be used as an internal microbial marker for the determination of microbial protein synthesis.

Application

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Related product

Č. produktu
Popis
Stanovení ceny

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Vyberte jednu z posledních verzí:

Osvědčení o analýze (COA)

Lot/Batch Number

Je nám líto, ale pro tento produkt momentálně nemáme COA k dispozici online.

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Guanine 98%

Sigma-Aldrich

G11950

Guanine

Thymine ≥99%

Sigma-Aldrich

T0376

Thymine

Adenosine ≥99%

Sigma-Aldrich

A9251

Adenosine

Determination of adenine, caffeine, theophylline and theobromine by HPLC with amperometric detection
Meyer A, et al.
Fresenius Journal of Analytical Chemistry, 356(3-4), 284-287 (1996)
Simultaneous determination of adenine and guanine in ruminant bacterial pellets by ion-pair HPLC
Moral dGP, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 826(1-2), 257-260 (2005)
Michinori Matsuo et al.
Journal of molecular and cellular cardiology, 38(6), 907-916 (2005-05-25)
ATP-sensitive potassium (K(ATP)) channels are regulated by adenine nucleotides to convert changes in cellular metabolic levels into membrane excitability. Hence, elucidation of interaction of SUR and Kir6.x with adenine nucleotides is an important issue to understand the molecular mechanisms underlying
Caroline Pabst et al.
Nature methods, 11(4), 436-442 (2014-02-25)
Leukemic stem cells (LSCs) are considered a major cause of relapse in acute myeloid leukemia (AML). Defining pathways that control LSC self-renewal is crucial for a better understanding of underlying mechanisms and for the development of targeted therapies. However, currently
Didier Wion et al.
Nature reviews. Microbiology, 4(3), 183-192 (2006-02-21)
N(6)-methyl-adenine is found in the genomes of bacteria, archaea, protists and fungi. Most bacterial DNA adenine methyltransferases are part of restriction-modification systems. Certain groups of Proteobacteria also harbour solitary DNA adenine methyltransferases that provide signals for DNA-protein interactions. In gamma-proteobacteria
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