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Key Documents

32347

Supelco

Validamycin A

PESTANAL®, analytical standard

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen


About This Item

Empirický vzorec (Hillův zápis):
C20H35NO13
Číslo CAS:
Molekulová hmotnost:
497.49
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental
forensics and toxicology
veterinary

format

neat

storage temp.

2-8°C

SMILES string

O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@@H](CO)C[C@H](N[C@H]3C=C(CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)O[C@H](CO)[C@H]1O

InChI

1S/C20H35NO13/c22-3-6-1-8(12(26)15(29)11(6)25)21-9-2-7(4-23)19(17(31)13(9)27)34-20-18(32)16(30)14(28)10(5-24)33-20/h1,7-32H,2-5H2/t7-,8+,9+,10-,11-,12+,13+,14-,15+,16+,17-,18-,19-,20+/m1/s1

InChI key

JARYYMUOCXVXNK-CSLFJTBJSA-N

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General description

Validamycin A is an antifungal aminoglycoside antibiotic produced by Streptomyces hygroscopicus. It is widely used as a plant protection reagent for the treatment of rice sheath blight disease in plants.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Validamycin A may be used as a reference standard in the determination of validamycin A in commercial products and food products using micellar electrokinetic capillary chromatographic technique (MEKC)and liquid chromatography coupled with atmospheric pressure chemical ionization–tandem mass spectrometry (LC–APCI–MS/MS).

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Osvědčení o analýze (COA)

Lot/Batch Number

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Potřebujete-li konkrétní verzi, můžete vyhledat daný certifikát podle čísla dávky nebo čísla šarže.

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Determination of the antibiotic fungicide validamycin A in formulated products by micellar electrokinetic chromatography.
Hsiao M-Y and Lo C-C
Journal of Agricultural and Food Chemistry, 47(9), 3723-3726 (1999)
Jae Jin Lee et al.
Nature communications, 10(1), 2928-2928 (2019-07-04)
Stochastic formation of Mycobacterium tuberculosis (Mtb) persisters achieves a high level of antibiotic-tolerance and serves as a source of multidrug-resistant (MDR) mutations. As conventional treatment is not effective against infections by persisters and MDR-Mtb, novel therapeutics are needed. Several approaches
Determination of validamycin A in agricultural food samples by solid-phase extraction combined with liquid chromatography?atmospheric pressure chemical ionisation?tandem mass spectrometry.
Wang C, et al.
Food Chemistry, 169, 150-155 (2015)
Qiong Wu et al.
Scientific reports, 7, 40140-40140 (2017-01-07)
Sheath blight, causes by Rhizoctonia spp., threaten maize yield every year throughout the world. Trichoderma could degrade Rhizoctonia solani on maize mainly via competition and hyperparasitism, whereas validamycin A could efficiently inhibit the growth of R. solani via disturbing the
Chenjiaozi Wang et al.
Fungal biology, 122(5), 322-332 (2018-04-19)
Rhizoctonia solani AG-1 IA is the causal agent of rice sheath blight (RSB) and causes severe economic losses in rice-growing regions around the world. The sclerotia play an important role in the disease cycle of RSB. In this study, we

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