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13180

Supelco

Benzylamine

for GC derivatization, LiChropur™, ≥99.0%

Synonyma:

α-Aminotoluene

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About This Item

Lineární vzorec:
C6H5CH2NH2
Číslo CAS:
100-46-9
Molekulová hmotnost:
107.15
Beilstein/REAXYS Number:
741984
EC Number:
202-854-1
MDL number:
MFCD00008106
UNSPSC Code:
12000000
eCl@ss:
39030404
PubChem Substance ID:
329750088
NACRES:
NA.22

grade

for GC derivatization

Quality Level

100

assay

≥99.0% (GC)
≥99.0%

form

liquid

quality

LiChropur™

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.543 (lit.)
n20/D 1.543

bp

184-185 °C (lit.)

mp

10 °C (lit.)

solubility

H2O: soluble

density

0.981 g/mL at 25 °C (lit.)

SMILES string

NCc1ccccc1

InChI

1S/C7H9N/c8-6-7-4-2-1-3-5-7/h1-5H,6,8H2

InChI key

WGQKYBSKWIADBV-UHFFFAOYSA-N

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General description

Benzylamine, a primary amine, can be used as a fluorescence derivatization agent for the sensitive and selective determination of analytes by chromatography techniques coupled with fluorescence detection.

Application

Benzylamine may be used as a derivatization agent to increase the sensitivity of 5-hydroxyindoles, catecholamines and catechols in biological samples prior to their determination using high performance liquid chromatography (HPLC) coupled with fluorescence detection.

Recommended products

Discover LiChropur™ reagents ideal for HPLC or LC-MS analysis

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 1

flash_point_f

149.0 °F - closed cup

flash_point_c

65 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Osvědčení o analýze (COA)

Lot/Batch Number
BCCM4389
BCCL4617
BCCK0792
BCCK6435
BCCH2116

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Sigma-Aldrich

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Sigma-Aldrich

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Simultaneous determination of norepinephrine, serotonin, and 5-hydroxyindole-3-acetic acid in microdialysis samples from rat brain by microbore column liquid chromatography with fluorescence detection following derivatization with benzylamine
Yoshitake T, et al.
Analytical Biochemistry, 312(2), 125-133 (2003)
The Derivatization of Proquinoidal Analytes with 1, 2-Diphenylethane-1, 2-Diamine (DPE) and Benzylamine (BA): An Investigation of Products, Yields, Kinetics and Reagent Selectivity
Woods JM, et al.
Chromatographia, 78(3-4), 163-178 (2015)
Kaoru Fujino et al.
Journal of chromatography. A, 1012(2), 169-177 (2003-10-03)
A highly selective and sensitive method for the simultaneous determination of 5-hydroxyindoles and catechols (serotonin, norepinephrine, dopamine and related compounds) by high-performance liquid chromatography with fluorescence detection is described. The method is based on the two-step precolumn derivatization of 5-hydroxyindoles
Saioa Gomez-Zorita et al.
Journal of physiology and biochemistry, 69(3), 585-593 (2013-01-15)
Resveratrol is a naturally occurring polyphenol found in many dietary sources and red wine. Recognized as a cancer chemoprevention agent, an anti-inflammatory factor and an antioxidant molecule, resveratrol has been proposed as a potential anti-obesity compound and to be beneficial
Hong Cao et al.
Organic letters, 13(1), 11-13 (2010-12-02)
A versatile synthesis of unsaturated seven-membered ring lactams has been developed. The sequence involves hydroamination of Baylis-Hillman acetate with amines, followed by intramolecular cyclocarbonylation reactions of the resulting allylamines. This process can tolerate a wide array of functional groups, and
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