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01580590

Ginsenoside Rf

primary reference standard

Synonyma:

(3β,6α,12β)-3,12,20-Trihydroxydammar-24-en-6-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside, Panaxoside Rf

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About This Item

Empirický vzorec (Hillův zápis):
C42H72O14
Číslo CAS:
52286-58-5
Molekulová hmotnost:
801.01
MDL number:
MFCD00210509
UNSPSC Code:
85151701
PubChem Substance ID:
329747330
NACRES:
NA.24

grade

primary reference standard

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

HWI

application(s)

food and beverages

storage temp.

−20°C

SMILES string

[H][C@]1(O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@@]2([H])O[C@H]3C[C@]4(C)[C@]([H])(C[C@@H](O)[C@]5([H])[C@]([H])(CC[C@@]45C)[C@@](C)(O)CC\C=C(/C)C)[C@@]6(C)CC[C@H](O)C(C)(C)[C@]36[H]

InChI

1S/C42H72O14/c1-20(2)10-9-13-42(8,52)21-11-15-40(6)28(21)22(45)16-26-39(5)14-12-27(46)38(3,4)35(39)23(17-41(26,40)7)53-37-34(32(50)30(48)25(19-44)55-37)56-36-33(51)31(49)29(47)24(18-43)54-36/h10,21-37,43-52H,9,11-19H2,1-8H3/t21-,22+,23-,24+,25+,26+,27-,28-,29+,30+,31-,32-,33+,34+,35-,36-,37+,39+,40+,41+,42-/m0/s1

InChI key

UZIOUZHBUYLDHW-XUBRWZAZSA-N

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Související kategorie

General description

Ginsenoside is a steroid-like molecular component having gonane steroid nucleus along with different sugar moieties attached to them found in the roots of Panax ginseng. Ginsenoside Rf, a variety of ginseng saponins with attached sugars moieties which inhibits the Ca2+ channels present in primary sensory neurons.
Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Application

It may be used as reference standard in HPLC-MS/MS analysis of human plasma to determine Ginsenosides from herbal products containing Panax ginseng and Panax quinquefolius.

Other Notes

This compound is commonly found in plants of the genus: panax

Pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Osvědčení o analýze (COA)

Lot/Batch Number
HWI02364
HWI01522-2
HWI01522-1
HWI01522
HWI01253-1

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Ginsenoside Rb2 analytical standard

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Ginsenoside Rb2

Ginsenoside Rb1 European Pharmacopoeia (EP) Reference Standard

Y0001347

Ginsenoside Rb1

J J Nah et al.
Biological & pharmaceutical bulletin, 23(5), 523-526 (2000-05-24)
A rapid and sensitive indirect competitive enzyme immunoassay method has been developed for quantitating ginsenoside Rf (Rf) in crude total Panax ginseng saponins and in rat plasma using high titer mouse monoclonal antibody (mAb) raised against a conjugate of Rf
Eun-Ah Bae et al.
Biological & pharmaceutical bulletin, 29(9), 1862-1867 (2006-09-02)
The inhibitory effects of the Korean red ginseng (steamed root of Panax ginseng C.A. MEYER, family Araliaceae) saponin fraction (KRGS) and its constituents ginsenosides Rg3, Rf, and Rh2 in mouse passive cutaneous anaphylaxis (PCA) and contact dermatitis models were measured.
De-qiang Dou et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 28(6), 522-524 (2004-03-16)
To isolate and elucidate the constituents from the roots of Commercial Ginseng. Column chromatography and HPLC were used to isolate chemical constituents. Physico-chemical characters and spectr-oscopic analysis were employed for structural identification. Sixteen compounds were identified as: notoginsenoside-R2(1), ginsenoside-Rg2(2), 20
Li Li et al.
Journal of pharmaceutical and biomedical analysis, 52(1), 66-72 (2010-01-19)
A new method using ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry (UPLC/Q-TOF-MS) was developed for the rapid qualitative and quantitative analyses of Asian ginseng (Panax ginseng C.A.Meyer) in adulterated American ginseng (Panax quinquefolium L.) preparations within 2min. The method was
Q C Ji et al.
Phytochemical analysis : PCA, 12(5), 320-326 (2001-11-14)
An HPLC-MS/MS method was developed for the quantitative determination of ginsenosides, which are the marker compounds for herbal products containing Panax ginseng (Korean or Chinese ginseng) and P. quinquefolius (American ginseng). Samples were extracted with BondElut C18 HF extraction columns
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Sortimentní položky

HPLC Separation: Ginsenosides from American Ginseng

Optimize HPLC method for ginsenoside separation using a mixture, applying it to American Ginseng root, with conditions and chromatograms shown.

High-Performance Thin-Layer Chromatography: A Fast and Efficient Fingerprint Analysis Method for Medicinal Plants

In this article we present several HPTLC applications and analytical standards for ginsenosides.

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