Přejít k obsahu
Merck
Všechny fotografie(1)

Key Documents

648471

Trolox

A cell-permeable, water-soluble derivative of vitamin E with antioxidant properties. Prevents peroxynitrite-mediated oxidative stress and apoptosis in rat thymocytes.

Synonyma:

Trolox, 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic Acid

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen


About This Item

Empirický vzorec (Hillův zápis):
C14H18O4
Číslo CAS:
Molekulová hmotnost:
250.29
MDL number:
UNSPSC Code:
12352205

assay

≥98% (titration)

form

powder

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white to off-white
white to pale green
white to pale yellow

solubility

water: 0.5 mg/mL (slightly soluble)
ethanol: 150 mg/mL
methanol: soluble

shipped in

ambient

storage temp.

2-8°C

InChI

1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)

InChI key

GLEVLJDDWXEYCO-UHFFFAOYSA-N

General description

A cell-permeable, water-soluble derivative of vitamin E with antioxidant properties. Prevents peroxynitrite-mediated oxidative stress and apoptosis in rat thymocytes.
A cell-permeable, water-soluble derivative of vitamin E with potent antioxidant properties. Prevents peroxynitrite-mediated oxidative stress and apoptosis in rat thymocytes.

Application


  • Structural characterization of peroxyl radical oxidative products of antioxidant peptides from hydrolyzed proteins.: This study highlights the application of Trolox in understanding the oxidative modifications of antioxidant peptides, which could help in the development of more effective antioxidative therapies and supplements (Esfandi et al., 2024).

  • Extraction of bioactive compounds from pecan nutshell: An added-value and low-cost alternative for an industrial waste.: Trolox is utilized to evaluate the antioxidant capacity of bioactive extracts from pecan shells, presenting a sustainable approach to utilizing agricultural waste (Cardona Jimenez et al., 2024).

  • Investigation into the role of carboxylic acid and phenolic hydroxyl groups in the plant biostimulant activity of a humic acid purified from an oxidized sub-bituminous coal.: Utilizing Trolox equivalent antioxidant capacity (TEAC) assay, this research explores the bio-stimulatory properties of humic substances, enhancing our understanding of their role in agriculture (Lamar et al., 2024).

Warning

Toxicity: Harmful (C)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Ethanol stock solutions are stable for up to 1 month at -20°C.

Other Notes

Salgo, M.G. and Pryor, W.A. 1996. Arch. Biochem. Biophys. 333, 482.
McClain, D.E., et al. 1995. FASEB J. 9, 1345.
Salgo, M.G., et al. 1995. Arch. Biochem. Biophys.322, 500.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Osvědčení o analýze (COA)

Vyhledejte osvědčení Osvědčení o analýze (COA) zadáním čísla šarže/dávky těchto produktů. Čísla šarže a dávky lze nalézt na štítku produktu za slovy „Lot“ nebo „Batch“.

Již tento produkt vlastníte?

Dokumenty související s produkty, které jste v minulosti zakoupili, byly za účelem usnadnění shromážděny ve vaší Knihovně dokumentů.

Navštívit knihovnu dokumentů

Meriam Missaoui et al.
Molecules (Basel, Switzerland), 25(9) (2020-05-10)
The Opuntia ficus indica (L.) (OFI) is used as a nutritional and pharmaceutical agent in various dietary and value added products. This study underlines the possible use of native prickly pear cladode powder as a functional ingredient for health-promoting food
Refat Aboghazleh et al.
International journal of molecular sciences, 22(21) (2021-11-14)
Traumatic brain injury (TBI) is the leading cause of death in young individuals, and is a major health concern that often leads to long-lasting complications. However, the electrophysiological events that occur immediately after traumatic brain injury, and may underlie impact
Saravanan Palani et al.
eLife, 10 (2021-07-17)
Actin filaments are central to numerous biological processes in all domains of life. Driven by the interplay with molecular motors, actin binding and actin modulating proteins, the actin cytoskeleton exhibits a variety of geometries. This includes structures with a curved
Ying-Nan Jiang et al.
Journal of ethnopharmacology, 256, 112824-112824 (2020-04-08)
Tianma Gouteng granules (TG), a clinical prescription of traditional Chinese medicine, has been clinically applied to treat Parkinson's disease (PD) in combination with Madopar, as included in the Chinese Pharmacopoeia (2015). TG has the potential to decrease the susceptibility of
Saara Hämälistö et al.
Nature communications, 11(1), 229-229 (2020-01-15)
Lysosomes are membrane-surrounded cytoplasmic organelles filled with a powerful cocktail of hydrolases. Besides degrading cellular constituents inside the lysosomal lumen, lysosomal hydrolases promote tissue remodeling when delivered to the extracellular space and cell death when released to the cytosol. Here

Náš tým vědeckých pracovníků má zkušenosti ve všech oblastech výzkumu, včetně přírodních věd, materiálových věd, chemické syntézy, chromatografie, analytiky a mnoha dalších..

Obraťte se na technický servis.