612075

Thyroxine-Binding Globulin, Human

Liver glycoprotein and a major thyroid hormone carrier in serum. Exhibits high sequence similarity with α1-antitrypsin.

• Synonyma: hTBG
• UNSPSC Code: 12352202
• NACRES: NA.25

Vlastnosti

• Quality Level: 100
• assay: ≥95.0% (SDS-PAGE)
• form: liquid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• shipped in: wet ice
• storage temp.: −20°C

Popis

General description

M.W. 54,000-64,000.

Native, human thyroxine-binding globulin. Liver glycoprotein and a major thyroid hormone carrier in serum. Exhibits high sequence similarity with α₁-antitrypsin. Its affinity for the hormone is thought to be temperature-sensitive.

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Physical form

In 140 mM NaCl, 10 mM Tris, 0.1% NaN₃, pH 8.0. Sterile-filtered.

Preparation Note

Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Miura, Y., et al. 1993. Endocrinol. J. 40, 127.
Janssen, O.E., et al. 1992. J. Biol. Chem.267, 13998.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Bezpečnostní informace

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable