444278-M

MMP-9 Inhibitor I

≥93% (HPLC), solid, MMP-9 inhibitor, Calbiochem^®

• Synonyma: MMP-9 Inhibitor I
• Empirický vzorec (Hillův zápis): C₂₇H₃₃N₃O₅S
• Číslo CAS: 1177749-58-4
• Molekulová hmotnost: 511.63
• UNSPSC Code: 12352200

Vlastnosti

• product name: MMP-9 Inhibitor I, MMP-9 Inhibitor I, CAS 1177749-58-4, is a cell-permeable, potent, and reversible MMP-9 Inhibitor (IC₅₀ = 5 nM). At high concentration inhibits MMP-1 (IC₅₀ = 1.05 µM) & MMP-13 (IC₅₀ = 113 nM).
• Quality Level: 100
• assay: ≥93% (HPLC)
• form: solid
• potency: 5 nM IC₅₀
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; protect from light
• color: off-white
• solubility: DMSO: 10 mg/mL
• storage temp.: −20°C

Popis

General description

A cell-permeable, potent, selective, and reversible MMP-9 Inhibitor (IC₅₀ = 5 nM). Inhibits MMP-1 (IC₅₀ = 1.05 µM) and MMP-13 (IC₅₀ = 113 nM) only at much higher concentrations.

A cell-permeable, potent, selective, and reversible inhibitor of MMP-9 (IC₅₀ = 5 nM). Also inhibits MMP-1 (IC₅₀ = 1.05 µM) and MMP-13 IC₅₀ = 113 nM) at higher concentrations.

Biochem/physiol Actions

Primary Target
MMP-9

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Other Notes

Levin, J.I., et al. 2001. Bioorg. Med. Chem. Lett.11, 2189.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Bezpečnostní informace

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable