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Key Documents

M-138

Supelco

Mephedrone hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirický vzorec (Hillův zápis):
C11H16ClNO
Číslo CAS:
Molekulová hmotnost:
213.70
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule D (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)

concentration

1.0 mg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

InChI

1S/C11H15NO.ClH/c1-8-4-6-10(7-5-8)11(13)9(2)12-3;/h4-7,9,12H,1-3H3;1H

Inchi Key

DLQZFTUKJGRPLZ-UHFFFAOYSA-N

General description

Mephedrone, also known as 4-methylmethcathinone, is a synthetic stimulant of the amphetamine and cathinone classes. Significant abuse of this new recreational drug has been reported within the last year in the UK; Sweden; and Toronto, Canada with confiscation of the drug in states including Oregon.

Application


  • Nanotube-based Sensors for Drug Molecule Discrimination: Mephedrone is studied for its interaction with nanotube-based sensors, enhancing the discrimination of drug molecules. This research is critical for developing new technologies in forensic science and drug abuse monitoring, providing high accuracy in identifying psychoactive substances (Algharagholy et al., 2023).

  • Environmental Monitoring of New Psychoactive Substances: Analytical methods including mephedrone have been developed for the simultaneous determination of 56 new psychoactive substances in surface water. This application is vital for environmental monitoring and understanding the ecological impact of synthetic cathinones, ensuring water safety and public health (Atasoy Aydin et al., 2023).

  • Supramolecular Hosts for In Vivo Sequestration: Research on supramolecular hosts capable of sequestering mephedrone and other stimulants like methamphetamine and fentanyl in vivo, provides significant advancements in therapeutic approaches for drug addiction and overdose treatment. This study paves the way for novel detoxification strategies using chemical sequestrants (Brockett et al., 2023).

  • SERS Substrates for Clinical Applications: Mephedrone has been examined in the development of ultrasensitive portable Surface-Enhanced Raman Scattering (SERS) substrates. These substrates are designed for rapid and precise clinical diagnostics, showcasing the potential of mephedrone in enhancing bioanalytical methods (Lin et al., 2023).

  • Forensic Differentiation of Isomers: Portable near-infrared spectroscopy has been utilized for the isomeric differentiation of mephedrone among new psychoactive substances. This technology is essential for law enforcement and forensic applications, providing a quick and non-destructive means to distinguish between drug isomers in field conditions (Kranenburg et al., 2022).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Application

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup


Osvědčení o analýze (COA)

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Navštívit knihovnu dokumentů

Priscilla B Pail et al.
Neurotoxicology, 50, 71-80 (2015-08-10)
Mephedrone and methedrone are cathinone-related compounds, which act as non-selective substrates for monoamine transporters, facilitating a neurotransmitter release. We compared the acute pharmacological effects of mephedrone and methedrone, attempting to further evaluate the action mechanisms of methedrone by responsibly and

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