870708P

08:0 Coenzyme A

Avanti Research^™ - A Croda Brand 870708P, powder

• Synonyma: octanoyl Coenzyme A (ammonium salt)
• Empirický vzorec (Hillův zápis): C₂₉H₅₉N₁₀O₁₇P₃S
• Číslo CAS: 799812-82-1
• Molekulová hmotnost: 944.82
• UNSPSC Code: 12352211
• NACRES: NA.25

Vlastnosti

• form: powder
• packaging: pkg of 1 × 5 mg (870708P-5mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 870708P
• application(s): lipidomics
• lipid type: coenzymes
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: O[C@@](C(NCCC(NCCSC(CCCCCCC)=O)=O)=O)(C(C)(COP([O-])(OP([O-])(OC[C@H]([C@H]1OP([O-])(O)=O)O[C@H]([C@@H]1O)N2C3=C(C(N)=NC=N3)N=C2)=O)=O)C)[H].[NH4+].[NH4+].[NH4+]
• InChI: 1S/C29H50N7O17P3S.3H3N/c1-4-5-6-7-8-9-20(38)57-13-12-31-19(37)10-11-32-27(41)24(40)29(2,3)15-50-56(47,48)53-55(45,46)49-14-18-23(52-54(42,43)44)22(39)28(51-18)36-17-35-21-25(30)33-16-34-26(21)36;;;/h16-18,22-24,28,39-40H,4-15H2,1-3H3,(H,31,37)(H,32,41)(H,45,46)(H,47,48)(H2,30,33,34)(H2,42,43,44);3*1H3/t18-,22?,23+,24+,28-;;;/m1.../s1
• InChI key: FTIQWXKUZWNHGD-DMTDIVBASA-N

Popis

General description

08:0 Coenzyme A, also referred as octanoyl Coenzyme A, is a medium-chain acyl CoA. It is a coenzyme A derivative of octanoic acid.

Application

08:0 Coenzyme A has been used as a substrate in microsomal ghrelin octanoyltransferase assay.

Biochem/physiol Actions

08:0 Coenzyme A acts as an intermediate in mitochondrial fatty acid β-oxidation. It hinders the activity of citrate synthase (CS) and glutamate dehydrogenase (GDH). Higher levels of octanoyl –CoA, due to reduced β-oxidation of octanoyl-CoA by medium-chain acyl CoA dehydrogenase (MCADH), is observed in patients with MCADH deficiency (MCD).

Packaging

5 mL Amber Glass Screw Cap Vial (870708P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Bezpečnostní informace

• Storage Class: 11 - Combustible Solids