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855675C

Avanti

16:0 Lyso PC

1-palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine, chloroform

Synonyma:

1-hexadecanoyl-sn-glycero-3-phosphocholine; PC(16:0/0:0)

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About This Item

Empirický vzorec (Hillův zápis):
C24H50NO7P
Číslo CAS:
17364-16-8
Molekulová hmotnost:
495.63
UNSPSC Code:
51191904
NACRES:
NA.25

assay

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (855675C-25mg)
pkg of 2 × 4 mL (855675C-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 855675C

concentration

10 mg/mL (855675C-25mg)
25 mg/mL (855675C-200mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCCCCCC)=O

InChI

1S/C24H50NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24(27)30-21-23(26)22-32-33(28,29)31-20-19-25(2,3)4/h23,26H,5-22H2,1-4H3/t23-/m1/s1

InChI key

ASWBNKHCZGQVJV-HSZRJFAPSA-N

Application

16:0 Lyso PC has been used to reveal the central role of the adipocyte inflammasome in homocysteine-induced insulin resistance. It has also been used for lipid extraction and mass spectrometry analysis.

Packaging

5 mL Clear Glass Sealed Ampule (855675C-200mg)
5 mL Clear Glass Sealed Ampule (855675C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk_germany

WGK 3

Osvědčení o analýze (COA)

Vyhledejte osvědčení Osvědčení o analýze (COA) zadáním čísla šarže/dávky těchto produktů. Čísla šarže a dávky lze nalézt na štítku produktu za slovy „Lot“ nebo „Batch“.

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846725C

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1-Stearoyl-sn-glycero-3-phosphocholine ≥99%, powder

Sigma-Aldrich

L2131

1-Stearoyl-sn-glycero-3-phosphocholine

16:0 PC (DPPC) Avanti Research™ - A Croda Brand

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850355C

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L-α-Lysophosphatidylcholine egg yolk, ≥99.0% (TLC)

Sigma-Aldrich

62962

L-α-Lysophosphatidylcholine

16:0-18:1 PC Avanti Research™ - A Croda Brand

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850457P

16:0-18:1 PC

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4-Aminoantipyrine reagent grade

Sigma-Aldrich

A4382

4-Aminoantipyrine

Song-Yang Zhang et al.
EBioMedicine, 31, 202-216 (2018-05-08)
The adipose Nod-like receptor protein 3 (NLRP3) inflammasome senses danger-associated molecular patterns (DAMPs) and initiates insulin resistance, but the mechanisms of adipose inflammasome activation remains elusive. In this study, Homocysteine (Hcy) is revealed to be a DAMP that activates adipocyte
Oxidized phospholipids inhibit the formation of cholesterol-dependent plasma membrane nanoplatforms
Brameshuber M, et al.
Biophysical Journal, 110(1), 205-213 (2016)
Takafumi Enomoto et al.
Langmuir : the ACS journal of surfaces and colloids, 34(3), 750-755 (2017-10-06)
A major goal of synthetic biology is the development of rational methodologies to construct self-assembling non-natural membranes, which could enable the efficient fabrication of artificial cellular systems from purely synthetic components. However, spatiotemporal control of artificial membrane formation remains both
Xinyuan Li et al.
Redox biology, 28, 101373-101373 (2019-11-16)
It has been shown that anti-inflammatory cytokines interleukin-35 (IL-35) and IL-10 could inhibit acute endothelial cell (EC) activation, however, it remains unknown if and by what pathways IL-35 and IL-10 could block atherogenic lipid lysophosphatidylcholine (LPC)-induced sustained EC activation; and
Li V Yang et al.
Blood, 105(3), 1127-1134 (2004-09-24)
G2A is a G-protein-coupled receptor (GPCR) involved in immune regulation. Previous studies have shown that lysophosphatidylcholine (LPC), a bioactive lipid associated with atherosclerosis and autoimmunity, acts through G2A to induce diverse biologic effects. Production of LPC during cell apoptosis serves
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