850755C

18:2 PE

1,2-dilinoleoyl-sn-glycero-3-phosphoethanolamine, chloroform

• Synonyma: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine; PE(18:2(9Z,12Z)/18:2(9Z,12Z))
• Empirický vzorec (Hillův zápis): C₄₁H₇₄NO₈P
• Číslo CAS: 20707-71-5
• Molekulová hmotnost: 740.00
• UNSPSC Code: 51191904
• NACRES: NA.25

Vlastnosti

• assay: >99% (TLC)
• form: liquid
• packaging: pkg of 1 × 2.5 mL (850755C-25mg); pkg of 2 × 4 mL (850755C-200mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 850755C
• concentration: 10 mg/mL (850755C-25mg); 25 mg/mL (850755C-200mg)
• lipid type: cardiolipins; phospholipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCC/C=C\C/C=C\CCCCC)=O
• InChI: 1S/C41H74NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h11-14,17-20,39H,3-10,15-16,21-38,42H2,1-2H3,(H,45,46)/b13-11-,14-12-,19-17-,20-18-/t39-/m1/s1
• InChI key: SSCDRSKJTAQNNB-DWEQTYCFSA-N

Popis

General description

Phosphatidylethanolamine (PE) is the second most plenteous glycerophospholipid in eukaryotic cells. It is a non-bilayer forming phospholipid, which is found majorly in the mitochondria. It consists of a small polar head group with fatty acid chains.

Application

18:2 PE has been used for the preparation of liposomes.

Biochem/physiol Actions

Phosphatidylethanolamine (PE) functions as to provide rigidity to the cell membranes via hexagonal phase structures which promote tight packing of the membrane bilayer formed by phosphatidylcholine. It is also involved in the conversion of prions from the non-toxic to toxic conformation. PE also initiates the autophagosome formation by attaching covalently to the autophagy Atg8 protein.

Packaging

5 mL Clear Glass Sealed Ampule (850755C-200mg)

5 mL Clear Glass Sealed Ampule (850755C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Bezpečnostní informace

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H302,H315,H319,H331,H336,H351,H361d,H372
• pcodes: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• target_organs: Liver,Kidney, Respiratory system
• Storage Class: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: does not flash
• flash_point_c: does not flash