850697P

06:0 PE

1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine, powder

• Synonyma: PE(6:0/6:0)
• Empirický vzorec (Hillův zápis): C₁₇H₃₄NO₈P
• Číslo CAS: 96893-06-0
• Molekulová hmotnost: 411.43
• UNSPSC Code: 51191904
• NACRES: NA.25

Vlastnosti

• assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 25 mg (850697P-25mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 850697P
• lipid type: cardiolipins; phospholipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCC)=O)COC(CCCCC)=O
• InChI: 1S/C17H34NO8P/c1-3-5-7-9-16(19)23-13-15(26-17(20)10-8-6-4-2)14-25-27(21,22)24-12-11-18/h15H,3-14,18H2,1-2H3,(H,21,22)/t15-/m1/s1
• Inchi Key: PELYUHWUVHDSSU-OAHLLOKOSA-N

Popis

General description

06:0 Phosphatidylethanolamine (PE) is a water-soluble short-chain glycero-phospholipid. It is primarily found in the inner leaflet of the plasma membrane.

Phosphatidylethanolamine (PE), an abundant phospholipid in the inner mitochondrial membrane accounts for 15–25% of the total lipid in the cells of mammals.

Application

06:0 PE (1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine/DHPE) may be used:

• as a substrate for glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP) in specificity assay
• as a phosphoethanolamine (PE) standard in liquid chromatographic analysis of milk phospholipids
• as a phospholipid substrate to study the kinetic parameters for the glucose transporter type 4 (Glu4) mutants

06:0 Phosphatidylethanolamine (PE) has been used as a ligand in the co-crystallization of broadly neutralizing anti-HIV antibody 4E10. It has also been used as one of the phospholipids (PLs) standards for the analysis of bovine milk PL classes by normal-phase high-performance liquid chromatography (NP-HPLC).

Biochem/physiol Actions

06:0 Phosphatidylethanolamine (PE) plays an important role in various cellular processes such as autophagy, cell division and protein folding. In addition it also acts as a precursor for the synthesis of several protein modifications and as an intermediate in the synthesis of other glycerophospholipids.

Phosphoethanolamine (PE) serves as a precursor in membrane phospholipid biosynthesis. Phosphatidylethanolamine controls membrane fluidity in eukaryotic cells.

Packaging

5 mL Clear Glass Sealed Ampule (850697P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Bezpečnostní informace

• Storage Class: 11 - Combustible Solids