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700126P

Avanti

campesterol

Avanti Research™ - A Croda Brand 700126P, powder

Synonyma:

campest-5-en-3β-ol

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen
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About This Item

Empirický vzorec (Hillův zápis):
C28H48O
Číslo CAS:
474-62-4
Molekulová hmotnost:
400.68
MDL number:
MFCD00670159
UNSPSC Code:
12352211
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (700126P-1mg)
pkg of 1 × 10 mg (700126P-10mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 700126P

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC1CCC2(C3C(C4C(C(CC4)C(CCC(C(C)C)C)C)(CC3)C)CC=C2C1)C

InChI

1S/C28H48O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h9,18-20,22-26,29H,7-8,10-17H2,1-6H3

InChI key

SGNBVLSWZMBQTH-UHFFFAOYSA-N

General description

Campesterol is a plant sterol, which is an analog of cholesterol and a brassinosteroid (BR) precursor. The enzyme diminute/dwarf1 mediates the synthesis of campesterol from 24-methylenecholesterol. Campesterol possesses methyl group at C-24 position of the side chain in the cholesterol structure.

Application

Campesterol may be used as a plant sterol to test its effect on the transcriptional activation of liver X receptor α (LXRA) in breast cancer cells. It may also be used as a sterol standard for calibration curve generation in liquid chromatography multiple reaction monitoring (LC-MRM) analysis.

Biochem/physiol Actions

Campesterol reduces the levels of chylomicron, low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL)-apoB100. A high ratio of campesterol to sitosterol enhances fiber elongation in cotton fibres.

Packaging

5 mL Amber Glass Screw Cap Vial (700126P-10mg)
5 mL Amber Glass Screw Cap Vial (700126P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

also commonly purchased with this product

Č. produktu
Popis
Stanovení ceny

700060P

desmosterol, Avanti Research™ - A Croda Brand

700062P

stigmasterol, Avanti Research™ - A Croda Brand

700095P

sitosterol, Avanti Research™ - A Croda Brand

700121P

sitostanol, β-sitostanol, powder

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Osvědčení o analýze (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Dokumenty section.

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β-Sitosterol synthetic, ≥95%

Sigma-Aldrich

S1270

β-Sitosterol

Δ 5-avenasterol Avanti Research™ - A Croda Brand

Avanti

700174P

Δ 5-avenasterol

Stigmasterol phyproof® Reference Substance

PHL82658

Stigmasterol

β-Sitosterol ≥70%

Sigma-Aldrich

85451

β-Sitosterol

β-Sitosterol from soybean, ≥96%

Sigma-Aldrich

S9889

β-Sitosterol

Cycloartenol ≥90% (GC)

Sigma-Aldrich

08172

Cycloartenol

Shasha Deng et al.
Science China. Life sciences, 59(2), 183-193 (2016-01-25)
Phytosterols play an important role in plant growth and development, including cell division, cell elongation, embryogenesis, cellulose biosynthesis, and cell wall formation. Cotton fiber, which undergoes synchronous cell elongation and a large amount of cellulose synthesis, is an ideal model
Laura Calpe-Berdiel et al.
Atherosclerosis, 203(1), 18-31 (2008-08-12)
Plant sterols and stanols (phytosterols/phytostanols) are known to reduce serum low-density lipoprotein (LDL)-cholesterol level, and food products containing these plant compounds are widely used as a therapeutic dietary option to reduce plasma cholesterol and atherosclerotic risk. The cholesterol-lowering action of
Samantha A Hutchinson et al.
International journal of molecular sciences, 20(13) (2019-07-05)
Low fruit and vegetable consumption and high saturated fat consumption causes elevated circulating cholesterol and are breast cancer risk factors. During cholesterol metabolism, oxysterols form that bind and activate the liver X receptors (LXRs). Oxysterols halt breast cancer cell proliferation
U Klahre et al.
The Plant cell, 10(10), 1677-1690 (1998-10-08)
We have identified the function of the Arabidopsis DIMINUTO/DWARF1 (DIM/DWF1) gene by analyzing the dim mutant, a severe dwarf with greatly reduced fertility. Both the mutant phenotype and gene expression could be rescued by the addition of exogenous brassinolide. Analysis
Michael Igel et al.
Journal of lipid research, 44(3), 533-538 (2003-02-04)
The recent identification of the aberrant transport proteins ABCG5 and ABCG8 resulting in sitosterolemia suggests that intestinal uptake of cholesterol is an unselective process, and that discrimination between cholesterol and plant sterols takes place at the level of sterol efflux
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