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QBD10773

Sigma-Aldrich

dPEG®24-biotin acid

>95% (HPLC)

Synonyma:

Biotin-PEG-acid, Biotin-PEG24-COOH, PEG1000 biotin acid, PEG24-biotin acid

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About This Item

Empirický vzorec (Hillův zápis):
C61H117N3O28S
Molekulová hmotnost:
1372.65
MDL number:
MFCD26793761
UNSPSC Code:
12352106
NACRES:
NA.22

assay

>95% (HPLC)

form

solid or viscous liquid

reaction suitability

reaction type: Biotinylations
reaction type: Pegylations

polymer architecture

shape: linear
functionality: monofunctional

shipped in

ambient

storage temp.

−20°C

SMILES string

S1C(C2NC(=O)NC2C1)CCCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O

InChI

1S/C61H117N3O28S/c65-58(4-2-1-3-57-60-56(55-93-57)63-61(68)64-60)62-6-8-70-10-12-72-14-16-74-18-20-76-22-24-78-26-28-80-30-32-82-34-36-84-38-40-86-42-44-88-46-48-90-50-52-92-54-53-91-51-49-89-47-45-87-43-41-85-39-37-83-35-33-81-31-29-79-27-25-77-23-21-75-

InChI key

ZDKCSORFFNBMQV-UHFFFAOYSA-N

Features and Benefits

dPEG24 biotin acid consists of a biotin molecule conjugated to a single molecular weight polyethylene glycol chain of discrete length (dPEG). The dPEG chain is 76 atoms (90.1 Å) long. The distal end of the dPEG chain terminates with a propionic acid group. The terminal acid is available for direct conjugation to free amines or functionalization as an active ester. Amphiphilic dPEG24 biotin acid can be dissolved both in water or aqueous buffer and in organic solvent. It does not cause aggregation or precipitation of biomolecules. Using 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) chemistry, dPEG24 biotin acid can be coupled directly to free primary amines in aqueous media. These free amines can be on a protein, peptide, or the treated surface of a nanoparticle. Moreover, the acid moiety can be functionalized with other reactive groups for coupling directly to surfaces such as glass, gold, or magnetic nanoparticles. The linker length of dPEG24 biotin acid is much longer than the linker lengths of LC-biotin and of LC-LC-biotin and is a monodisperse equivalent of a PEG1000. The performance characteristics of dPEG24-biotin acid are quite superior to both LC-biotin and LC-LC-biotin.

Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002)

Legal Information

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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