A48105

Cycloleucine

97%

• Synonyma: 1-Aminocyclopentanecarboxylic acid
• Lineární vzorec: H₂NC₅H₈CO₂H
• Číslo CAS: 52-52-8
• Molekulová hmotnost: 129.16
• Beilstein/REAXYS Number: 636626
• EC Number: 200-144-6
• MDL number: MFCD00001381
• UNSPSC Code: 12352209
• PubChem Substance ID: 24890914
• NACRES: NA.22

Vlastnosti

• assay: 97%
• form: crystals
• reaction suitability: reaction type: solution phase peptide synthesis
• technique(s): ligand binding assay: suitable
• mp: 320 °C (dec.) (lit.)
• application(s): peptide synthesis
• SMILES string: NC1(CCCC1)C(O)=O
• InChI: 1S/C6H11NO2/c7-6(5(8)9)3-1-2-4-6/h1-4,7H2,(H,8,9)
• InChI key: NILQLFBWTXNUOE-UHFFFAOYSA-N

Popis

General description

Cycloleucine is a nonmetabolizable amino acid widely used as a building block in peptide synthesis.

Application

Cycloleucine can be used as a building block to synthesize:

• Phosphonylmethylaminocyclopentane-1-carboxylic acid by reacting with paraformaldehyde and diethylphosphite via Kabachnik-Field′s reaction.
• Benzo[b]thiophene-2-carboxylic acid {1-[1-(R)-(3-morpholin-4-ylpropylcarbamoyl)-2-phenylethylcarbamoyl]cyclopentyl}-amide, (MEN14268) as potential tachykinin NK2 receptor antagonist.

Bezpečnostní informace

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P301 + P310 + P330
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves