923834
Chitosan-mPEG 1k
25-60% PEGylation, medium MW
Synonyma:
Medium MW, PEGylated Chitosan
Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen
About This Item
Lineární vzorec:
(C8H13NO5)p((C2H4O)nC10H17NO6)m
UNSPSC Code:
12352201
NACRES:
NA.23
Doporučené produkty
Application
- Chitosan has in the last decades been widely used in a variety of applications, both industrially and pharmaceutically.
- Its positive charges under slightly acidic conditions allow it to form complexes or nanoparticles.
- During the delivery process, the stable compact structure of the complex, with cationic chitosan chains as the outershell and the anionic genes/drugs as the core, efficiently protects genes/drugs from the ″sweeping effect″ of mucociliary clearance and degradation by enzymes.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Vyberte jednu z posledních verzí:
Osvědčení o analýze (COA)
Lot/Batch Number
Nevidíte správnou verzi?
Potřebujete-li konkrétní verzi, můžete vyhledat daný certifikát podle čísla dávky nebo čísla šarže.
Již tento produkt vlastníte?
Dokumenty související s produkty, které jste v minulosti zakoupili, byly za účelem usnadnění shromážděny ve vaší Knihovně dokumentů.
Peggy Chan et al.
Biomaterials, 28(3), 540-549 (2006-09-27)
Poor water solubility and low transfection efficiency of chitosan are major drawbacks for its use as a gene delivery carrier. PEGylation can increase its solubility, and folate conjugation may improve gene transfection efficiency due to promoted uptake of folate receptor-bearing
PEGylated chitosan derivatives:Synthesis, characterizations and pharmaceutical applications
Casettarietal L, et al.
Progress in Polymer Science, 37, 659-685 (2012)
Li Xiang et al.
Physical chemistry chemical physics : PCCP, 21(37), 20571-20581 (2019-08-01)
PEGylation can modify the physicochemical properties of native chitosan and improves its water solubility. PEGylated chitosan has been widely used as a gene/drug delivery vector by forming a polyelectrolyte complex (PEC) in biomedical engineering. The molecular interactions of PEGylated chitosan
H Ragelle et al.
Journal of controlled release : official journal of the Controlled Release Society, 176, 54-63 (2014-01-07)
This study aims at developing chitosan-based nanoparticles suitable for an intravenous administration of small interfering RNA (siRNA) able to achieve (i) high gene silencing without cytotoxicity and (ii) stability in biological media including blood. Therefore, the influence of chitosan/tripolyphosphate ratio
Náš tým vědeckých pracovníků má zkušenosti ve všech oblastech výzkumu, včetně přírodních věd, materiálových věd, chemické syntézy, chromatografie, analytiky a mnoha dalších..
Obraťte se na technický servis.