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51126

Sigma-Aldrich

Hyamine® 1622 solution

4 mM in H2O

Synonyma:

(Diisobutylphenoxyethoxyethyl)dimethylbenzylammonium chloride solution

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About This Item

Číslo CAS:
121-54-0
Beilstein/REAXYS Number:
3898548
MDL number:
MFCD00011742
UNSPSC Code:
12352112
PubChem Substance ID:
57651278
NACRES:
NA.22

concentration

4 mM in H2O

density

0.998 g/mL at 20 °C

SMILES string

[Cl-].CC(C)(C)CC(C)(C)c1ccc(OCCOCC[N+](C)(C)Cc2ccccc2)cc1

InChI

1S/C27H42NO2.ClH/c1-26(2,3)22-27(4,5)24-13-15-25(16-14-24)30-20-19-29-18-17-28(6,7)21-23-11-9-8-10-12-23;/h8-16H,17-22H2,1-7H3;1H/q+1;/p-1

InChI key

UREZNYTWGJKWBI-UHFFFAOYSA-M

General description

Hyamine® 1622 is a cationic detergent benzethonium chloride. Poly(vinyl chloride) membrane ion-selective electrode for the Hyamine 1622 cation has been proposed. Its sorption on soil surfaces has been investigated. It is widely used in cosmetics and shampoos due to its antimicrobial and cationic surfactant properties.

Application

Hyamine® 1622 solution was used as surfactant to examine its acute toxicity and effect on oxidative stress and cholinesterase (ChE) activity in Dugesia japonica. It may be employed as stopping reagent in the improved Eliman procedure for erythrocyte cholinesterase.

Legal Information

Hyamine is a registered trademark of Lonza Group Ltd.

hcodes

H412

Hazard Classifications

Aquatic Chronic 3

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

Osvědčení o analýze (COA)

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Poly (vinyl chloride) containing dibenzo-18-crown-6 as an ion-selective membrane for hyamine 1622.
Khalil MM, et al.
Analytical Letters, 19(7-8), 807-824 (1986)
Mei-Hui Li
Chemosphere, 70(10), 1796-1803 (2007-10-02)
Eight widely used surfactants (cetyltrimethylammonium bromide; CTAB, benzethonium chloride; Hyamine 1622, 4-nonylphenol; NP, octylphenol ethoxylate; Triton X-100, dodecylbenzene sulfonate; LAS, lauryl sulfate; SDS, pentadecafluorooctanoic acid; PFOA, and perfluorooctane sulfonate; PFOS) were selected to examine their acute toxicities and effects on
Sorption of anionic surfactants SDS, AOT and cationic surfactant Hyamine 1622 on natural soils.
Atay N, et al.
Water, Air, Soil Pollut., 136(1-4), 55-68 (2002)
P M George et al.
Clinical chemistry, 29(2), 365-368 (1983-02-01)
The procedure of Dietz et al. (Clin. Chem. 19: 1309-1313, 1973) for plasma cholinesterase (EC 3.1.1.7) gives a background absorbance of 1.4 A when extended to erythrocyte cholinesterase (EC 3.1.1.8) measurement, because the peak absorbance of the reaction product, 5-thionitrobenzoate
Elisabeth Lang et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 28(2), 347-354 (2011-08-26)
Benzethonium, an antimicrobial surfactant widely used as preservative of pharmaceuticals, topical wound care product and oral disinfectant, triggers apoptosis of several cell types. The apoptosis is preceded and possibly triggered by mitochondrial depolarization. Even though lacking mitochondria, erythrocytes may similarly
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