374881

4-Chloro-3-(trifluoromethyl)phenyl isocyanate

98%

• Lineární vzorec: ClC₆H₃(CF₃)NCO
• Číslo CAS: 327-78-6
• Molekulová hmotnost: 221.56
• NACRES: NA.22
• PubChem Substance ID: 24863347
• UNSPSC Code: 12352100
• MDL number: MFCD00013874
• Assay: 98%

Vlastnosti

• Quality Segment: 100
• assay: 98%
• bp: 86-90 °C/14 mmHg (lit.)
• mp: 40-42 °C (lit.)
• functional group: chloro, fluoro, isocyanate
• SMILES string: FC(F)(F)c1cc(ccc1Cl)N=C=O
• InChI: 1S/C8H3ClF3NO/c9-7-2-1-5(13-4-14)3-6(7)8(10,11)12/h1-3H
• InChI key: NBJZEUQTGLSUOB-UHFFFAOYSA-N

Popis

General description

4-Chloro-3-(trifluoromethyl)phenyl isocyanate participates in an efficient methodology for the synthesis of 5-methyl-3-aryl-2-thiooxazolidin-4-ones.

Application

4-Chloro-3-(trifluoromethyl)phenyl isocyanate may be used in the synthesis of:

• N-(5′-deoxy-3′-O-tert-butyldimethylsilyl-β-D-thymidin-5′-yl)-N′-(4-chloro-3-trifluoromethylphenyl)-thiourea
• [1,3-bis(4-chloro-α,α,α-trifluoro-m-tolyl)urea]
• trans-1-(4-chloro-3-trifluoromethyl-phenyl)-3-(4-hydroxy-cyclohexyl)-urea

Bezpečnostní informace

• pictograms: GHS08,GHS05,GHS07
• signalword: Danger
• hcodes: H302 + H312 + H332,H315,H317,H318,H334,H335
• pcodes: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• Skladovací třída: 11 - Combustible Solids
• flash_point_f: 210.2 °F - closed cup
• flash_point_c: 99 °C - closed cup
• ppe: dust mask type N95 (US), Eyeshields, Gloves