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Key Documents

200689

Sigma-Aldrich

Ethyl cellulose

viscosity 10 cP, 5 % in toluene/ethanol 80:20(lit.), extent of labeling: 48% ethoxyl

Synonyma:

ethylcellulose

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About This Item

Číslo CAS:
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.23

form

powder

autoignition temp.

698 °F

extent of labeling

48% ethoxyl

refractive index

n20/D 1.47 (lit.)

viscosity

10 cP, 5 % in toluene/ethanol 80:20(lit.)

transition temp

softening point 155 °C

density

1.14 g/mL at 25 °C (lit.)

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General description

Ethyl cellulose(EC) is a hydrophobic andphysiologically inert cellulose derivative. It is widely used to preparephysiological dosage forms. It can also be used as a polymer coating,particle emulsion stabilizer and in pharmaceuticallyuseful aqueous latex dispersions.

Application

Ethyl cellulose can be used as a starting material to prepare zein-based nanofibers for controlled drug release. The addition of EC improves the solubility and mechanical properties of the composite nanofibers.

It can be used to prepare graphene-based ink for inkjet printing. This graphene oxide ink printed onto ITO surfaces can be used as an electrode for label-free DNA sensing.

Owing to its unique features such as gastroresistance, biocompatibility, and degradation to non-toxic and readily excreted products, EC is widely used in oral and topical drug dosage forms for the controlled release of the drug.

Features and Benefits

  • Non-toxic
  • Stable
  • Compressible

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Arif Z Nelson et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(11), 5671-5679 (2020-03-05)
Microfluidic tools and techniques for manipulating fluid droplets have become core to many scientific and technological fields. Despite the plethora of existing approaches to fluidic manipulation, non-Newtonian fluid phenomena are rarely taken advantage of. Here we introduce embedded droplet printing-a
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International journal of pharmaceutics, 438(1-2), 150-159 (2012-09-12)
The potential of excipient coating to enhance aerosol performance of micronized drugs in carrier excipient-drug blends, used in dry powder inhalers, was investigated. Both EC (ethyl cellulose) and PVP (polyvinylpyrrolidone) were used as coating agents. Carriers were prepared via sieve
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European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 82(3), 485-490 (2012-09-08)
The phytochemical curcumin possesses antioxidant activity; however, it becomes unstable after being exposed to light or heat or loses activity during storage. This is especially important when curcumin is applied to the skin within a cosmetic or pharmaceutical formulation, since
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Pakistan journal of pharmaceutical sciences, 25(4), 751-756 (2012-09-27)
The aim and objective of the present study was to formulate and evaluate controlled release polymeric tablets of ibuprofen with determinations of formulation factors using various grades and types of polymer ethocel i.e. ethocel standard 10P; 10FP, 100P and100FP for
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Production of drug nanoparticles is an effective strategy to enhance solubility and oral absorption of water-insoluble drugs. The handling of drug nanoparticles has been an important issue in drug formulation because nanoparticles easily aggregate each other and redispersion of these

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