1250008

β-Estradiol

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: β-Estradiol, 1,3,5-Estratriene-3,17β-diol, 17β-Estradiol, 3,17β-Dihydroxy-1,3,5(10)-estratriene, Dihydrofolliculin
• Fórmula empírica (notación de Hill): C₁₈H₂₄O₂
• Número de CAS: 50-28-2
• Peso molecular: 272.38
• Beilstein: 1914275
• Número MDL: MFCD00003693
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329749749
• NACRES: NA.24

Propiedades

• grado: pharmaceutical primary standard
• familia API: estradiol
• fabricante / nombre comercial: USP
• mp: 176-180 °C (lit.)
• aplicaciones: pharmaceutical (small molecule)
• Formato: neat
• cadena SMILES: O[C@H]1CC[C@@]2([H])[C@]3([H])CCC4=CC(O)=CC=C4[C@@]3([H])CC[C@@]21C
• InChI: 1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
• Clave InChI: VOXZDWNPVJITMN-ZBRFXRBCSA-N
• Información sobre el gen: human ... ESR1(2099)

Descripción

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Acciones bioquímicas o fisiológicas

The major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female phenotype in embryogenesis and during puberty by regulating gene transcription and, thus, protein synthesis. It also induces the production of gonadotropins which, in turn, induce ovulation. Exposure to estradiol increases breast cancer incidence and proliferation.

The major estrogen secreted by the premenopausal ovary.

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS08,GHS09
• Palabra de señalización: Danger
• Frases de peligro: H351,H360FD,H362,H410
• Consejos de prudencia: P201 - P202 - P260 - P263 - P273 - P308 + P313
• Clasificaciones de peligro: Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Lact. - Repr. 1A
• Código de clase de almacenamiento: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable